Category Biology/Biotechnology

Cholesterol may Not be the Only Lipid involved in Trans Fat-driven Cardiovascular Disease

Cholesterol is not the only lipid involved in trans fat-driven cardiovascular disease
Graphical abstract. Credit: Cell Metabolism (2024). DOI: 10.1016/j.cmet.2024.10.016

Excess cholesterol is known to form artery-clogging plaques that can lead to stroke, arterial disease, heart attack, and more, making it the focus of many heart health campaigns. Fortunately, this attention to cholesterol has prompted the development of cholesterol-lowering drugs called statins and lifestyle interventions like dietary and exercise regimens. But what if there’s more to the picture than just cholesterol?

New research from Salk Institute scientists describes how another class of lipids, called sphingolipids, contributes to arterial plaques and atherosclerotic cardiovascular disease (ASCVD)...

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Minimally Invasive Neural Interface Allows Brain Access Without Skull Opening

jacob robinson
Their experiments showed that the catheter electrodes could be successfully delivered and guided into the ventricular spaces and brain surface for electrical stimulation. Image courtesy of Rice University.

A team of researchers led by Rice University’s Jacob Robinson and the University of Texas Medical Branch’s Peter Kan has developed a technique for diagnosing, managing and treating neurological disorders with minimal surgical risks. The team’s findings were published in Nature Biomedical Engineering.

While traditional approaches for interfacing with the nervous system often require creating a hole in the skull to interface with the brain, the researchers have developed an innovative method known as endocisternal interfaces (ECI), allowing for electrical recording and stimulation o...

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New miRNA Inhibitor could Extinguish the ‘Inflammatory Fire’ that Stroke causes in the Brain

It’s been more than three decades, but still there are only two treatments for a stroke: either rapid use of a clot-busting medication called tPA or surgical removal of a clot from the brain with mechanical thrombectomy. However, only 5% to 13% percent of stroke cases are actually eligible for these interventions.

“We need to be persistent with our research to find a new therapy for stroke,” says Rajkumar Verma, M.Pharm., Ph.D., assistant professor, Department of Neuroscience at UConn School of Medicine working in cross-campus collaboration with Professor Raman Bahal Ph.D. of the Department of Pharmaceutical Sciences in the UConn School of Pharmacy. “Stroke research is hard and challenging to do. But without trying we won’t make progress. We need to keep trying...

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Standing Desks are Bad for your Health, according to a new study

standing desk
Credit: Pixabay/CC0 Public Domain

The global market for standing desks is booming, projected to reach US$12.6 billion by 2032 (£9.7 billion). These desks have been hailed as a simple fix for the health risks associated with sitting all day. However, recent research suggests that standing might not be the health booster many hoped for.

A new study from Australia involving over 83,000 participants found that prolonged standing may not improve heart health and could even increase the risk of certain circulatory problems.

Researchers discovered that standing for extended periods did not reduce the risk of heart disease and stroke...

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