Category Biology/Biotechnology

Medherant Patch. Credit: Image courtesy of University of Warwick

It delivers drug directly via skin to where needed at a consistent dose rate. Researchers at the University of Warwick have worked with Coventry-based Medherant, a Warwick spinout company in developing a transparent adhesive patch that can consistently deliver a prolonged high dose of the painkiller ibuprofen directly through the skin. The University of Warwick researchers and Medherant have found a way to incoporate significant amounts of the drug (up to 30% weight) into the polymer matrix that sticks the patch to the patient’s skin with the drug then being delivered at a steady rate over up to 12 hours...

Ebselen affects the phosphoinositide cycle and has CNS effects on surrogate markers that may be relevant to the treatment of bipolar disorder, which can be tested in future clinical trials.

A drug destined for the scrap heap has been rescued by Oxford scientists. They used a database of ‘failed’ drugs, found to be safe but ineffective for their proposed use, to identify ebselen as a possible alternative to lithium, the main treatment for people who are bipolar.

Ebselen was under development as a treatment for stroke, but was abandoned by its manufacturer in the final phase of clinical trials. However, those trials proved that the drug was safe for use in humans. Initial tests of ebselen as a treatment for bipolar disorder were carried out in mice...

Illustration depicting biocell attached to CMOS integrated circuit with membrane containing sodium-potassium pumps in pore. Credit: Trevor Finney and Jared Roseman/Columbia Engineering

System combines biological ion channels with solid-state transistors to create a new kind of electronics. Researchers have, for the first time, harnessed the molecular machinery of living systems to power an integrated circuit from ATP, energy currency of life. They integrated a conventional solid-state complementary metal-oxide-semiconductor (CMOS) integrated circuit with an artificial lipid bilayer membrane with ATP-powered ion pumps, opening the door to creating entirely new artificial systems that contain both biological and solid-state components.

“We are excited at the prospect of expanding the palette...

As far as healthy foods go, berries make the top of the list. They contain potent antioxidants, which decrease or reverse the effects of free radicals. Unsurprisingly, the benefits of berries are extoled in one study after another. It is usually the exotic Goji, Acerola or Acai berries that make the headlines as Superfoods, but for the health-savvy European consumer the native homegrown species could be even more alluring.The research suggests that black raspberries grown in Central Europe show greater health benefits than their better known cousins – raspberries or blackberries.

A group of researchers led by Anna Małgorzata Kostecka-Gugała measured the content of phenolics and anthocyanins in black raspberries, red raspberries and blackberries, assessing their antioxidant potential ...