Category Biology/Biotechnology

3D Printing method capable of Producing Highly Uniform ‘Blocks’ of Embryonic Stem Cells

Schematic representation of this research.

Schematic representation of this research.

These cells – capable of generating all cell types in the body – could be used as the ‘Lego bricks’ to build tissue constructs, larger structures of tissues, and potentially even micro-organs. “It was really exciting to see that we could grow embryoid body in such a controlled manner,” explains Wei Sun. “The grown embryoid body is uniform and homogenous, and serves as a much better starting point for further tissue growth.”

The researchers, based at Tsinghua University, Beijing, China, and Drexel University, Philadelphia, USA, used extrusion-based 3D printing to produce a grid-like 3D structure to grow embryoid body with cell viability and rapid self-renewal for 7 days while maintaining high pluripotentcy.

Images of the printed cellular model with grid structure. (A) Full view of the cellular construct. (B) Phase-contrast images demonstrating the cell morphology and distribution of different cell density at day 3, day 5 and day 7. Scale bar: 1 mm.

Images of the printed cellular model with...

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‘Magic’ Plant discovery could lead to Growing Food in Space

QUT researchers Dr Julia Bally and Professor Peter Waterhouse have discovered a plant with huge genome properties that can have the potential to be the 'laboratory rat' of the molecular plant world. This could open the door for such things as space-based food production Credit: Erika Fish

QUT researchers Dr Julia Bally and Professor Peter Waterhouse have discovered a plant with huge genome properties that can have the potential to be the ‘laboratory rat’ of the molecular plant world. This could open the door for such things as space-based food production Credit: Erika Fish

Professor Peter Waterhouse, a plant geneticist at QUT, discovered the gene in the ancient Australian native tobacco plant Nicotiana benthamiana, known as Pitjuri to Aboriginals.

Prof Waterhouse made the discovery while tracing the history of the Pitjuri plant, which for decades has been used by geneticists as a model plant upon which to test viruses and vaccines. “This plant is the ‘laboratory rat’ of the molecular plant world,” he said, “we think of it as a magical plant with amazing properties.

“We now ...

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130yo debate gives new Rx direction. Right side of Brain can compensate for Post-Stroke Loss of Speech

Broca's area , wernicke's area, and other language-processing areas in the brain

Broca’s area , wernicke’s area, and other language-processing areas in the brain

Researchers at Georgetown University Medical Center have found that loss of speech from a stroke in the left hemisphere of the brain can be recovered on the back, right side of the brain. This contradicts recent notions that the right hemisphere interferes with recovery. While the findings will likely not put an immediate end to the debate, they suggest a new direction in treatment.

This is the first to look at brain structure and grey matter volume when trying to understand how speech is recovered after a stroke...

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Sugar, Silicone & 3D Printer used to create an Implant with an Intricate Blood Vessel network for growing Transplant tissues & organs

Samantha Paulsen, a bioengineering graduate student in Jordan Miller's lab at Rice University, holds a plate on which several of 3-D-printed silicone constructs have been mounted. The constructs, which are each about the size of a small candy gummy bear, have been injected with red dye to better show the network of small vessels inside. Credit: Jeff Fitlow/Rice University

Samantha Paulsen, a bioengineering graduate student in Jordan Miller’s lab at Rice University, holds a plate on which several of 3-D-printed silicone constructs have been mounted. The constructs, which are each about the size of a small candy gummy bear, have been injected with red dye to better show the network of small vessels inside. Credit: Jeff Fitlow/Rice University

It may provide a method to overcome one of the biggest challenges in regenerative medicine: How to deliver oxygen and nutrients to all cells in an artificial organ or tissue implant that takes days or weeks to grow in the lab prior to surgery. The study showed blood flowed normally through test constructs that were surgically connected to native blood vessels.

Miller said one of the hurdles of engineering large artificial...

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