Category Health/Medical

Boosting good gut bacteria population through targeted interventions may slow cognitive decline

Boosting good gut bacteria population through targeted interventions may slow cognitive decline
Microbiota-targeted interventions are associated with improvements in memory, executive function, and global cognition. Credit: Darryl Leja, National Human Genome Research Institute, National Institutes of Health

The origin of neurodegenerative diseases like Alzheimer’s or dementia isn’t limited to the brain. The state of your gut can quietly set off a cycle of chronic, system-wide inflammation that nudges the brain toward cognitive decline. But how does the pathogenesis of a disease that seems purely brain-based begin in the gut—an organ that is mostly busy producing chemicals for digesting food?

It turns out these two entities are linked by the gut-brain axis, a two-way communication superhighway that constantly sends signals between the digestive tract and the central nervous s...

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Stroke triggers a hidden brain change that looks like rejuvenation

Stroke May Rejuvenate the Brain
When a stroke damages brain tissue along an important movement pathway, the injured side of the brain may show faster aging (red), while parts of the opposite side may appear relatively “younger” (blue) as the brain tries to compensate. This pattern is linked to more severe movement problems and less recovery. Credit: Stevens INI

Stroke may secretly “rejuvenate” parts of the brain as it fights to recover.
After a stroke, the brain may do something surprisingly hopeful—it can “refresh” parts of itself. Researchers analyzing brain scans from over 500 stroke survivors found that while the damaged side of the brain appears to age faster, the opposite, unaffected side can actually look younger...

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Implantable islet cells could control diabetes without insulin injections

Two tiny rectangular devices have curved edges. The devices are orange-yellow and are made of a circuit board and soldered pieces, including a diamond-shaped piece of material in the middle.
Caption:MIT engineers designed an implantable device that carries hundreds of thousands of islet cells along with its own on-board oxygen factory to keep the cells healthy.
Credits:Image: Felice Frankel

Most diabetes patients must carefully monitor their blood sugar levels and inject insulin multiple times per day, to help keep their blood sugar from getting too high. As a possible alternative to those injections, MIT researchers are developing an implantable device that contains insulin-producing cells. The device encapsulates the cells, protecting them from immune rejection, and it also carries an onboard oxygen generator to keep the cells healthy.

This device, the researchers hope, could offer a way to achieve long-term control of type 1 diabetes...

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Hair-thin fiber-optic sensors could detect cancer by reading multiple biomarkers

Tiny sensors with the power to detect cancer
A fibre-optic probe with 3D micro-printed sensing structures is immersed in a liquid sample, where light-induced emission reveals changes in the chemical environment in real time. Credit: University of Adelaide

Microscopic sensors that are as thin as a strand of hair but capable of taking multiple measurements simultaneously could revolutionize the diagnosis and monitoring of diseases like cancer. Researchers from Adelaide University’s Institute for Photonics and Advanced Sensing and the University of Stuttgart in Germany worked together to develop the tiny sensors using state-of-the-art, ultrafast 3D microprinting technology.

The unique sensors target specific biomarkers and are printed directly onto the tip of optical fibers...

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