Category Health/Medical

A new study in Aging Cell describes how a key protein called Signal Transducer and Activator of Transcription 3 (STAT3) might turn back the clock on aging cartilage that leads to osteoarthritis.

“STAT3 performs an astonishing repertoire of roles in development and regeneration, as well as inflammatory disease and cancer. In this study, we found an innovative chemical approach for reversing aging of joint-forming cells in a clinically relevant manner, because this intervention is simple and fully controlled,” said the study’s co-corresponding author Denis Evseenko, who is a Professor of Orthopaedic Surgery, and Stem Cell Biology and Regenerative Medicine at USC, and holds the J. Harold and Edna LaBriola Chair in Genetic Orthopedic Research.

“We wanted to ...

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), working in collaboration with institutes in the U.S., has demonstrated that acquired mutations in the gene encoding the protein p53 contribute to the development of atherosclerotic cardiovascular disease.

Known as the “guardian of the genome,” p53 helps to maintain the integrity of the hereditary material inside cells by regulating multiple cell functions in response to cellular stresses.

Every day, an adult person generates hundreds of thousands of blood cells...

Findings suggest new approach to treating Alzheimer’s, other neurodegenerative diseases. Gut bacteria can influence brain health, according to a study of mice genetically predisposed to develop Alzheimer’s-like brain damage...

A new study demonstrates that electrodes can be made using just screen printing, creating a stretchable, durable circuit pattern that can be transferred to fabric and worn directly on human skin. Such wearable electronics can be used for health monitoring in hospitals or at home. Current commercial manufacturing of wearable electronics requires expensive processes involving clean rooms. While some use screen printing for parts of the process, this new method relies wholly on screen printing, which can make manufacturing flexible, wearable electronics much easier and less expensive.

The glittering, serpentine structures that power wearable electronics can be created with the same technology used to print rock concert t-shirts, new research shows.