Category Health/Medical

Machine Learning Model builds on Imaging Methods to better Detect Ovarian Lesions

ultrasound images or a benign and a malignant lesion using Zhu's new technique
(From left) The top row shows an ultrasound image of a malignant lesion, the blood oxygen saturation, and hemoglobin concentration. The bottom row is an ultrasound image of a benign lesion, the blood oxygen saturation, and hemoglobin concentration. (Image: Zhu lab)

New research yields a novel method to use ultrasound to enhance machine learning’s ability to accurately diagnose — or rule out — ovarian cancer.

Although ovarian cancer is the deadliest type of cancer for women, only about 20% of cases are found at an early stage, as there are no real screening tests for them and few symptoms to prompt them...

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Team creates Nano-Magnets that could Restore Damaged Nerve Cells

The nano-magnets that will restore damaged nerve cells
Modular magnetic devices for applying local magnetic fields. Applying magnetic fields using A) 4 mm diameter pinhole parallelly-aligned and beehive-like magnetic devices. B) 1.5 cm diameter ring magnet. i) Illustrations of magnetic devices. In blue: pores are arranged in a beehive-like pattern, in red: pores are arranged in parallel lines. ii) Life-size images of magnetic rod/ring. iii) Simulations of magnetic flux density in COMSOL software. The images present a top view of magnetic flux density generated by a magnetic rod/ring in tesla (T). Intensity is color-coded (low intensity in dark blue, high intensity in red). iv) COMSOL simulations of magnetic field, magnetic flux density, and magnetic force 1 mm above the magnetic rod/ring. The magnetic field is indicated as solid lines...
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Chemotherapy could Increase Disease Susceptibility in Future Generations

An illustration of a cancer cell surrounded by healthy cells.
An illustration of a cancer cell among healthy cells. Image by CIPhotos on iStock.

A common chemotherapy drug could carry a toxic inheritance for children and grandchildren of adolescent cancer survivors, Washington State University-led research indicates. The study, published online in iScience, found that male rats who received the drug ifosfamide during adolescence had offspring and grand-offspring with increased incidence of disease. While other research has shown that cancer treatments can increase patients’ chance of developing disease later in life, this is one of the first-known studies showing that susceptibility can be passed down to a third generation of unexposed offspring.

“The findings suggest that if a patient receives chemotherapy, and then later has children, that t...

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Powerful New Tool to Advance Genomics, Disease Research

Powerful new tool to advance genomics, disease research
Image: Intrinsic cleavage biases affect single-cell ATAC-seq data analysis. Visualization of intrinsic cleavage bias effect in different cell clusters derived from scATAC-seq data for different biological samples and different experimental platforms: human hematopoietic cells (a–c), mixed human cell lines (d–f), mouse primitive gut tube (g–i), and 10× Single-Cell Multiome data for mouse embryonic brain (j–l), human peripheral blood mononuclear cells (PBMC) (m–o), and human lymph node (p–r). a, d, g, j, m, p UMAP visualization where cells are colored by cell type/labels/clusters. b, e, h, k, n, q Same UMAP visualization but cells are colored by cell bias score (CBS). c, f, i, l, o, r CBS distributions of cells from different cell types/batches/clusters...
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