Category Health/Medical

Common Gene Variant Linked to COVID Mortality

tavazoieostendorf
Sohail Tavazoie (left) and Benjamin Ostendorf (right).

Because three percent of the world population possesses these gene variants, the findings may have implications for hundreds of millions of individuals around the world

It may be the most baffling quirk of COVID: What manifests as minor, flu-like symptoms in some individuals spirals into severe disease, disability, and even death in others. A new paper published in Nature may explain the genetic underpinnings of this dichotomy.

The researchers demonstrated that mice with gene variants previously linked to Alzheimer’s disease were at greater risk of dying when infected with COVID. And a retrospective analysis suggests that patients with those same gene variants were more likely to have died of COVID throughout the pandemic...

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Simple 20-20-20 Screen Rule really does Help with Eye Strain, Research Shows

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Credit: Unsplash/CC0 Public Domain

It’s long been recommended as a way of easing eye strain while working at a computer screen. Now the 20-20-20 rule—taking a break of at least 20 seconds, every 20 minutes, to look at least 20 feet away—has been confirmed by scientists at Aston University to help ease some of the symptoms of prolonged computer use.

It’s estimated that at least half of people using computers in their regular work have some form of digital eye strain, resulting in eye surface problems including irritation and dryness, or vision issues such as headaches or blurred vision. Humans normally blink around 15 times each minute. When staring at screens, this number decreases generally to half that rate or less...

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High-Fat Diets Trigger Inflammatory Immune Cell Generation in Bone

High-fat diets drive the production of inflammatory immune cells in the bone  marrow of mice
High-fat diets trigger inflammatory immune cell generation in bone

A study suggests that high-fat diets fuel the creation of inflammatory immune cells in the bone marrow of mice. The results may help explain how high-fat diets trigger inflammation, which can contribute to the development of insulin resistance, type 2 diabetes and other complications in individuals with obesity.

An invasion of inflammatory immune cells, called monocytes, into fat tissue is a hallmark of obesity, but what leads to this harmful phenomenon is unclear. Many immune cells, including monocytes, are produced in the bone marrow, which is very sensitive to environmental changes. Scientists have already shown that fat cells in the bone marrow rapidly expand in response to a high-fat diet.

“We wanted to know ...

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Rheumatoid Arthritis Drug Effective against Myasthenia Gravis

Efficacy and Safety of Rituximab for New-Onset Generalized Myasthenia Gravis
Efficacy and Safety of Rituximab for New-Onset Generalized Myasthenia Gravis

Early intervention with rituximab, a drug used in the treatment of rheumatoid arthritis (RA), can reduce the risk of deterioration in myasthenia gravis, an autoimmune disease that causes loss of muscle control. This is according to a randomized clinical study led by researchers at Karolinska Institutet in Sweden and published in the journal JAMA Neurology.

“Patients with new onset myasthenia who received rituximab as a complement to standard of care showed greater improvement compared with patients who were given a placebo,” says Fredrik Piehl, professor at the Department of Clinical Neuroscience, Karolinska Institutet, and the study’s principal investigator...

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