Category Health/Medical

Patients are 20% less likely to die of sepsis because a new AI system developed at Johns Hopkins University catches symptoms hours earlier than traditional methods, an extensive hospital study demonstrates.

The system, created by a Johns Hopkins researcher whose young nephew died from sepsis, scours medical records and clinical notes to identify patients at risk of life-threatening complications. The work, which could significantly cut patient mortality from one of the top causes of hospital deaths worldwide, is published today in Nature Medicine and npj Digital Medicine.

“It is the first instance where AI is implemented at the bedside, used by thousands of providers, and where we’re seeing lives saved,” said Suchi Saria, founding research director of the Malone Center for Engin...

Going to the doctor might make you want to cry, and according to a new study, doctors could someday put those tears to good use. In ACS Nano, researchers report a nanomembrane system that harvests and purifies tiny blobs called exosomes from tears, allowing researchers to quickly analyze them for disease biomarkers. Dubbed iTEARS, the platform could enable more efficient and less invasive molecular diagnoses for many diseases and conditions, without relying solely on symptoms.

Diagnosing diseases often hinges on assessing a patient’s symptoms, which can be unobservable at early stages, or unreliably reported...

Eating chocolate is typically discouraged by nutritionists, as it is can be high in calories, fat and sugar. Cocoa, however, chocolate’s primary ingredient derived from the seed of the cacao plant, has been found to have numerous qualities that could be beneficial for both the body and mind.

Most notably, pure cocoa is highly nutritious and is a powerful source of antioxidants, substances that can prevent or slow down cell damage caused by free radicals. Free radicals are unstable and highly reactive molecules produced by the body when responding to environmental stresses, which are associated with aging and disease. In addition, cocoa has been found to help regulate the blood pressure and prevent cognitive decline.

Despite these potentially beneficial properties, chocolate bars...

Yale scientists have developed a novel omicron-specific mRNA vaccine that offers superior immune protection against two viral subvariants than standard mRNA vaccines.

The new vaccine, called Omnivax, increased neutralizing antibody response against the BA.1 and BA.2.12.1 omicron subvariants in pre-immunized mice 19-fold and eight-fold, respectively, compared with standard mRNA vaccines. The improved response against the BA.1 subvariant was reported June 6 in the journal Nature Communications. The results of the study involving the BA.2 subvariant were published July 19 in the journal Cell Discovery.

“While standard mRNA vaccines still offer protection against infection from new variants, their effectiveness wanes over time and was compromised due...