Category Health/Medical

Breast Duct Treatment for Early Breast Cancer Eliminates all Signs of Disease in Laboratory Experiments

Dr. Guannan Wang performs intraductal injection under a microscope. Credit: Qinxin Jiang

Next step is to study in women receiving mastectomy. Delivering a targeted immunotoxin into breast ducts via openings in the nipple wiped out all visible and invisible precancerous lesions in laboratory studies, led by researchers at the Johns Hopkins Kimmel Cancer Center, of very early stage breast cancers.

A description of the work performed on mice, which the authors say provides a strong pre-clinical foundation for conducting feasibility and safety trials with patients who have stage 0 breast cancers, is published in the June 8 issue of the Proceedings of the National Academy of Sciences.

Stage 0 breast cancer, also known as ductal carcinoma in situ (DCIS), is characterized as the presenc...

Read More

COVID-19 Rebound after taking Paxlovid likely due to Insufficient Drug Exposure, study finds

Human lung epithelial cells (blue) infected by SARS-CoV-2 BA.2 virus (red) isolated from a patient with COVID-19 rebound after Paxlovid treatment.

Paxlovid rebound patient did not show drug resistance or impaired immunity. Paxlovid is the leading oral medication for preventing severe cases of COVID-19 in high-risk individuals. However, symptoms returned in some patients after treatment was completed, prompting the Centers for Disease Control and Prevention (CDC) to issue a health advisory on this so-called “COVID-19 rebound.”

In a study published June 20, 2022 in Clinical Infectious Diseases, researchers at University of California San Diego School of Medicine evaluated one such patient and found their symptom relapse was not caused by the development of resistance to the drug or im...

Read More

Single Brain Scan can Diagnose Alzheimer’s disease

A single MRI scan of the brain could be enough to diagnose Alzheimer’s disease, according to new research by Imperial College London.

The research uses Machine Learning technology to look at Structural features within the brain, including in regions not previously associated with Alzheimer’s. The advantage of the technique is its simplicity and the fact that it can identify the disease at an early stage when it can be very difficult to diagnose.

Although there is no cure for Alzheimer’s disease, getting a diagnosis quickly at an early stage helps patients. It allows them to access help and support, get treatment to manage their symptoms and plan for the future...

Read More

COVID-19 on the brain: Neurological Symptoms Persist in Majority of Long-Haulers

Study: Evolution of neurologic symptoms in non-hospitalized COVID-19 “long haulers.” Image Credit: fizkes / Shutterstock.com

Longitudinal study describes short- and long-term neurological symptoms of SARS-CoV-2 infection; identifies new subgroup with advanced symptoms. Researchers at University of California San Diego School of Medicine are conducting a longitudinal study to track neurological symptoms in COVID-19 “long-haulers.”

The first round of results, published June 15, 2022 in Annals of Clinical and Translational Neurology, revealed the prevalence of various short- and long-term symptoms and found that, while many patients showed improvement, the majority still had some neurological symptoms after six months...

Read More