Category Health/Medical

Biodegradable Gel boosts Immune System’s Attack on Several Cancers in Mice

A high-magnification of the hydrogel (in blue) encapsulating T cell-activating platelets (in red) and nanoparticles that release a drug to inhibit tumor-boosting cells (in green). This gel inhibited the growth of cancer cells after surgical removal of different types of tumors. Credit: UW–Madison

A new biodegradable gel improves the immune system’s ability to keep cancer at bay after tumors are surgically removed. The gel, tested in mice, releases drugs and special antibodies that simultaneously deplete immune-blocking cells called macrophages from the surgical site and activate Tcells so they can attack cancer.

University of Wisconsin–Madison scientists tested the gel on mouse models of several cancers...

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Sugar-Coated Nanoparticles Target Macrophages, Reverse Pulmonary Fibrosis

Stock: sugar, granulated sugar, white sugar (https://pixabay.com/images/id-2510536/)

Nanoparticle platform delivers a nucleotide that blocks production of scar-promoting protein. Scientists at the University of Illinois Chicago have developed a treatment for pulmonary fibrosis by using nanoparticles coated in mannose — a type of sugar — to stop a population of lung cells called macrophages that contribute to lung tissue scarring. The cell-targeting method holds promise for preventing this severe lung scarring disease, which can result in life-threatening complications like shortness of breath.

The researchers say that the treatment is not yet ready to be tested in clinical trials, but its success in relevant animal models is a promising sign that it may be possible to treat the dise...

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Honey holds Potential for Making Brain-like Computer Chips

Photo by Mariana Ibanez on Unsplash

Honey might be a sweet solution for developing environmentally friendly components for neuromorphic computers, systems designed to mimic the neurons and synapses found in the human brain. Hailed by some as the future of computing, neuromorphic systems are much faster and use much less power than traditional computers. WSU Engineers have demonstrated one way to make them more organic too by using honey to make a memristor, a component similar to a transistor that can not only process but also store data in memory.

In a study published in Journal of Physics D, the researchers show that honey can be used to make a memristor, a component similar to a transistor that can not only process but also store data in memory.

“This is a very small device wi...

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Loss of Neurons, Not Lack of Sleep, makes Alzheimer’s Patients Drowsy

Neurons that promote wakefulness in the brain of an Alzheimer’s patient (green). There are far fewer functioning neurons that would be seen in a healthy brain, indicating that the awake system is weakened in this patient. Image by Grinberg Lab

Reviving ‘awake neurons’ could be the solution to their sleepiness. The lethargy that many Alzheimer’s patients experience is caused not by a lack of sleep, but rather by the degeneration of a type of neuron that keeps us awake, according to a study that also confirms the tau protein is behind that neurodegeneration.

The study’s findings contradict the common notion that Alzheimer’s patients sleep during the day to make up for a bad night of sleep and point toward potential therapies to help these patients feel more awake.

The data came fro...

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