Category Health/Medical

COVID-19 Can Trigger Self-Attacking Antibodies

Photo by Getty Images.
An illustration of antibodies (Y-shaped) responding to SARS-CoV-2 (orange), the novel coronavirus that causes COVID-19.

Infection with the virus that causes COVID-19 can trigger an immune response that lasts well beyond the initial infection and recovery—even among people who had mild symptoms or no symptoms at all, according to Cedars-Sinai investigators. The findings are published in the Journal of Translational Medicine.

When people are infected with a virus or other pathogen, their bodies unleash proteins called antibodies that detect foreign substances and keep them from invading cells. In some cases, however, people produce autoantibodies that can attack the body’s own organs and tissues over time.

The Cedars-Sinai investigators found that people w...

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Scientists identify Antibodies that can Neutralize Omicron

COVID-19 virus SARS-COV-2 OMICRON strain, covid-19 South African variant B.1.1.529 omicron 3d rendering

An international team of scientists have identified antibodies that neutralize omicron and other SARS-CoV-2 variants. These antibodies target areas of the virus spike protein that remain essentially unchanged as the viruses mutate.

By identifying the targets of these “broadly neutralizing” antibodies on the spike protein, it might be possible to design vaccines and antibody treatments that will be effective against not only the omicron variant but other variants that may emerge in the future, said David Veesler, investigator with the Howard Hughes Medical Institute and associate professor of biochemistry at the University of Washington School of Medicine in Seattle...

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Disarming a Blood-Clotting Protein Prevents Gum Disease in mice

Compared to healthy volunteers (left), gum tissue from people with severe periodontal disease (right) shows high levels of fibrin (magenta). Lakmali Silva, NIDCR

Human and animal study offers insight into treating periodontal disease and other inflammatory disorders. Blocking function of a blood-clotting protein prevented bone loss from periodontal (gum) disease in mice, according to research led by scientists at the National Institute of Dental and Craniofacial Research (NIDCR), part of the National Institutes of Health. Drawing on animal and human data, the researchers found that buildup of the protein, called fibrin, triggers an overactive immune response that damages the gums and underlying bone...

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Dietary Fiber improves outcomes for Melanoma Patients on Immunotherapy

Examples of dietary fiber, photo provided by NIH

Melanoma patients receiving therapy that makes it easier for their immune system to kill cancer cells respond to treatment better when their diet is rich in fiber, according to a large, international research collaboration that includes the Oregon State University College of Pharmacy.

Published today in Science, the study led by the University of Texas and the National Institutes of Health is a promising development in the fight against multiple types of cancer including melanoma, the most deadly form of skin cancer, the researchers said.

Nationwide, melanoma is the fifth-most common cancer...

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