Category Health/Medical

Disarming a Blood-Clotting Protein Prevents Gum Disease in mice

Compared to healthy volunteers (left), gum tissue from people with severe periodontal disease (right) shows high levels of fibrin (magenta). Lakmali Silva, NIDCR

Human and animal study offers insight into treating periodontal disease and other inflammatory disorders. Blocking function of a blood-clotting protein prevented bone loss from periodontal (gum) disease in mice, according to research led by scientists at the National Institute of Dental and Craniofacial Research (NIDCR), part of the National Institutes of Health. Drawing on animal and human data, the researchers found that buildup of the protein, called fibrin, triggers an overactive immune response that damages the gums and underlying bone...

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Dietary Fiber improves outcomes for Melanoma Patients on Immunotherapy

Examples of dietary fiber, photo provided by NIH

Melanoma patients receiving therapy that makes it easier for their immune system to kill cancer cells respond to treatment better when their diet is rich in fiber, according to a large, international research collaboration that includes the Oregon State University College of Pharmacy.

Published today in Science, the study led by the University of Texas and the National Institutes of Health is a promising development in the fight against multiple types of cancer including melanoma, the most deadly form of skin cancer, the researchers said.

Nationwide, melanoma is the fifth-most common cancer...

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Mapping the Musical Mind

Flat mind vision with music instrument and modern device. Concept woman person character with headphones, music plate and double bass. Vector illustration.

Interesting patterns of brain activity emerge during musical analysis exercises. Researchers in Japan used magnetic resonance imaging to study the brains of secondary school students during a task focused on musical observation. They found that students trained to play music from a young age exhibited certain kinds of brain activity more strongly than other students. The researchers also observed a specific link between musical processing and areas of the brain associated with language processing for the first time.

Professor Kuniyoshi L...

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People with IBD have more Microplastics in their Feces

Higher numbers of microplastics of various shapes, such as sheets (left) and fibers (right) were found in the feces of people with IBD than in healthy controls.
Credit: Adapted from Environmental Science & Technology 2021, DOI: 10.1021/acs.est.1c03924

Microplastics — tiny pieces of plastic less than 5 mm in length — are everywhere, from bottled water to food to air. According to recent estimates, people consume tens of thousands of these particles each year, with unknown health consequences. Now, researchers reporting in ACS’ Environmental Science & Technology found that people with inflammatory bowel disease (IBD) have more microplastics in their feces than healthy controls, suggesting that the fragments could be related to the disease process.

The prevalence of IBD, which includes ...

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