Category Health/Medical

An Estrogen Receptor that Promotes Cancer also Causes Drug-Binding Protein.

Three-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image by NIH

Cancer cells proliferate despite a myriad of stresses — from oxygen deprivation to chemotherapy — that would kill any ordinary cell. Now, researchers at UC San Francisco have gained insight into how they may be doing this through the downstream activity of a powerful estrogen receptor. The discovery offers clues to overcoming resistance to therapies like tamoxifen that are used in many types of breast cancer.

Estrogen receptor α (ERα) drives more than 70 percent of breast cancers. The new research published Sept...

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Tuning Flexible Circuits with Light

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Schematic showing the process that allows for precise control of the organic transistor characteristics using light irradiation. The inset displays a photograph of the final device. (credit: Takafumi Uemura et al.)

Researchers from SANKEN (The Institute of Scientific and Industrial Research) at Osaka University and JOANNEUM RESEARCH (Weiz, Austria), have shown how exposing an organic polymer to ultraviolet light can precisely modify its electronic properties. This work may aid in the commercialization of flexible electronics that can be used for real-time healthcare monitoring, along with data processing.

While the integrated circuits inside your smart phone are quite impressive, they lack certain important features...

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Intermittent Fasting can help Manage Metabolic Disease

Popular diet trend could reduce the risk of diabetes and heart disease. Eating your daily calories within a consistent window of 8-10 hours is a powerful strategy to prevent and manage chronic diseases such as diabetes and heart disease, according to a new manuscript published in the Endocrine Society’s journal, Endocrine Reviews.

Time-restricted eating is a type of intermittent fasting that limits your food intake to a certain number of hours each day. Intermittent fasting is one of the most popular diet trends, and people are using it to lose weight, improve their health and simplify their lifestyles.

“People who are trying to lose weight and live a healthier lifestyle should pay more attention to when they eat as well as what they eat...

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Sonic Hedgehog Protein Pathway Stimulation could help Parkinson’s Patients

A new study from Malave et al. suggests that in the brains of L-Dopa-treated Parkinson’s patients the lack of Shh signaling to cholinergic neurons results in L-Dopa induced dyskinesia. Image credit: Santiago Uribe-Cano

Levodopa, or L-dopa, is considered the most effective treatment for Parkinson’s disease today. After a few years of treatment, however, almost all patients develop a debilitating side-effect called L-dopa induced dyskinesia, or LID, which causes involuntary movements in the limbs, face, and torso. Deep brain stimulation can alleviate LID, but the procedure is highly invasive and not all patients are eligible.

Now, a new study led by researchers at the Graduate Center, CUNY and the CUNY School of Medicine shows that drugs that increased signaling by a protein called ...

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