Category Health/Medical

Red Blood Cell Alterations contribute to Lupus

Mitochondria (labeled with anti-COXIV antibody) can be detected in lupus red blood cells (labeled with Band-3 antibody) but not in healthy red blood cells.

The autoimmune disease lupus may be triggered by a defective process in the development of red blood cells (RBCs), according to a study led by researchers at Weill Cornell Medicine. The discovery could lead to new methods for classifying and treating patients with this disease.

The researchers, who published their findings August 11 in Cell, found that in a number of lupus patients, maturing red blood cells fail to get rid of their mitochondria — tiny molecular reactors that help convert oxygen into chemical energy in most cell types, but are normally excluded from red blood cells...

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New findings on How Ketamine Prevents Depression

Illustration of depression.
Illustration: Getty Images.

The discovery that the anaesthetic ketamine can help people with severe depression has raised hopes of finding new treatment options for the disease. Researchers at Karolinska Institutet in Sweden have now identified novel mechanistic insights how the drug exerts its antidepressant effect. The findings have been published in the journal Molecular Psychiatry.

According to the World Health Organization, depression is a leading cause of disability worldwide and the disease affects more than 360 million people every year.

The risk of suffering is affected by both genetics and environmental factors. The most commonly prescribed antidepressants, such as SSRIs, affect nerve signalling via monoamines in the brain...

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New Technology Paves Way towards Personalized Antibiotic Therapy

Lab technicians holding up portable and reusable microwave sensor
Using microwave sensing technology, UBCO researchers have developed a low-cost, contactless, portable and reusable microwave sensor that acts as a fast and reliable evaluation tool for measuring antibiotic resistance.

New sensor provides quick test to measure antibiotic resistance. UBC researchers have developed a method for monitoring bacterial responses to antibiotics in health-care settings that opens the door to personalized antibiotic therapy for patients.

Using microwave sensing technology, UBC Okanagan Assistant Professor Mohammad Zarifi and his team at the Okanagan Microelectronics and Gigahertz Applications (OMEGA) Lab have developed a low-cost, contactless, portable and reusable microwave sensor that acts as a fast and reliable evaluation tool for measuring antibiotic resi...

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New study offers Insight on how Resistance Training Burns Fat

Mongkolchon Akesin, iStock/Getty Images Plus
Mongkolchon Akesin, iStock/Getty Images Plus

Findings from a new University of Kentucky College of Medicine and College of Health Sciences study add to growing evidence that resistance exercise has unique benefits for fat loss. The Department of Physiology and Center for Muscle Biology study published in the FASEB Journal found that resistance-like exercise regulates fat cell metabolism at a molecular level.

The study results in mice and humans show that in response to mechanical loading, muscle cells release particles called extracellular vesicles that give fat cells instructions to enter fat-burning mode.

Extracellular vesicles were initially understood as a way for cells to selectively eliminate proteins, lipids and RNA...

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