Category Health/Medical

Biomarker could help to Diagnose Pancreatic Cancer

Studies have identified biomarkers that may be useful in diagnosing  pancreatic cancer - Florida News Times

Researchers from Queen Mary University of London have identified a protein that could be used to aid in the diagnosis of pancreatic cancer.

Findings from the new study suggest that a protein called pentraxin 3 (PTX3) may be a specific diagnostic biomarker — or biological measure — for pancreatic cancer, with the ability to differentiate pancreatic cancer from other non-cancerous conditions of the pancreas.

The research was published today in npj Precision Oncology, and primarily funded by the Pancreatic Cancer Research Fund, Barts Charity and Cancer Research UK.

PTX3 levels elevated in patients with pancreatic cancer

In the study, researchers measured PTX3 levels in serum blood samples from patients with pancreatic ductal adenocarcinoma (PDAC) — the most common type of pan...

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Being Clean and Hygienic Need Not Impair Childhood Immunity

The theory that modern society is too clean, leading to defective immune systems in children, should be swept under the rug, according to a new study by researchers at UCL and the London School of Hygiene & Tropical Medicine.

In medicine, the ‘hygiene hypothesis’ states that early childhood exposure to particular microorganisms protects against allergic diseases by contributing to the development of the immune system.

However, there is a pervading view (public narrative) that Western 21st century society is too hygienic, which means toddlers and children are likely to be less exposed to germs in early life and so become less resistant to allergies.

In this paper, published in the Journal of Allergy and Clinical Immunology, researchers point to four significant reasons which, ...

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Fibromyalgia likely the result of Autoimmune Problems

Passive transfer of fibromyalgia symptoms from patients to miceJournal of Clinical Investigation, 2021; 131 (13) DOI: 10.1172/JCI144201

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London, in collaboration with the University of Liverpool and the Karolinska Institute, has shown that many of the symptoms in fibromyalgia syndrome (FMS) are caused by antibodies that increase the activity of pain-sensing nerves throughout the body.

The results show that fibromyalgia is a disease of the immune system, rather than the currently held view that it originates in the brain.

The study, published today in the Journal of Clinical Investigation, demonstrates that the increased pain sensitivity, muscle weakness, reduced movement, and reduc...

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Newly Discovered Proteins Protect against Progression of Diabetic Kidney Disease

The cumulative incidence of End Stage Renal Disease (ESRD) according to index of protection of three proteins, Index=0/3 indicates no protection whereas Index=3/3 indicates full protection
The cumulative incidence of End Stage Renal Disease (ESRD) according to index of protection of three proteins, Index=0/3 indicates no protection whereas Index=3/3 indicates full protection

Elevated levels of three specific circulating proteins are associated with protection against kidney failure in diabetes, according to research from the Joslin Diabetes Center that will be published 30th June in Science Translational Medicine.

“As well as acting as biomarkers for advancing kidney disease risk in diabetes, the proteins may also serve as the basis for future therapies against progression to the most serious types of kidney disease,” said Andrzej S. Krolewski MD, Ph.D...

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