Category Health/Medical

A Novel Method for the Rapid Repair of Peripheral Nerve Injuries

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Researchers have developed nerve guidance conduits filled with smart gel that accelerate regeneration of torn nerve fibers. Each year, hundreds of thousands of people worldwide suffer from peripheral nerve injuries, which often leave them with long-term disabilities. The peripheral nervous system is analogous to the circulatory system; a network of vessels that reaches all parts of the body, but instead of blood flowing through vessels, electrical signals propagate information through thin fibers called axons, which are engulfed within nerve trunks. These nerve trunks are the communication network relaying information from all parts of the body to the brain, coordinating activity, and generating motor and sensory function...

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Antibiotics may help to treat Melanoma

Eleonora Leucci: “We need more research and clinical studies to examine the use of antibiotics to treat cancer patients.” The electron microscopy image above represents a human mitochondrion, the ‘power plant’ of the cell. Image created by Roberto Vendramin. 

Some antibiotics appear to be effective against a form of skin cancer known as melanoma. Researchers at KU Leuven, Belgium, examined the effect of these antibiotics on patient-derived tumours in mice. Their findings were published in the Journal of Experimental Medicine.

Researchers from KU Leuven may have found a new weapon in the fight against melanoma: antibiotics that target the ‘power plants’ of cancer cells. These antibiotics exploit a vulnerability that arises in tumour cells when they try to survive cancer therapy.

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Neurotransmitter Levels Predict Math Ability

Neurotransmitter levels predict math ability
Scanning was completed both during Time 1 and Time 2 (approximately 1.5 years later) in each of the 5 age groups (6-year-olds, 10-year-olds, 14-year-olds, 16-year-olds, and 18+-year-olds). Credit: Zacharopoulos G, et al., 2021, PLOS Biology

The neurotransmitters GABA and glutamate have complementary roles—GABA inhibits neurons, while glutamate makes them more active. Published 22nd July in PLOS Biology, researchers led by Roi Cohen Kadosh and George Zacharopoulos from the University of Oxford show that levels of these two neurotransmitters in the intraparietal sulcus of the brain can predict mathematics ability. The study also found that the relationships between the two neurotransmitters and arithmetic fluency switched as children developed into adults.

Levels of brain excitement...

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Study finds unleashing Treg cells may lead to Treatments for Multiple Sclerosis

Genetic deletion of Piezo1 in T cells leads to protection in autoimmunity: In the absence of Piezo1, Tregs expand more and, due to their increased numbers, are more effective in containing the damage inflicted by the effector T cells during an autoimmune neuroinflammation. Effector T cell function is not affected in the absence of Piezo1.
CREDIT
UCI School of Medicine

In a new University of California, Irvine-led study, researchers found that a certain protein prevented regulatory T cells (Tregs) from effectively doing their job in controlling the damaging effects of inflammation in a model of multiple sclerosis (MS), a devastating autoimmune disease of the nervous system.

Published this month in Science Advances, the new study illuminates the important role of Piezo1, a specialized p...

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