Category Health/Medical

Fat around the Heart Linked to Increased Risk of Heart Failure

Having excess pericardial fat — fat aro-und the heart — increases the risk of developing heart failure, especially in women, according to new Mount Sinai research.

Women with high amounts of pericardial fat are twice as likely to develop heart failure, while men are 50 percent more likely, according to the study, published in the May 24 online issue of the Journal of the American College of Cardiology. It is the largest study to identify the link between pericardial fat and heart failure, which could potentially lead to early intervention and heart disease prevention.

“For nearly two decades we have known that obesity, based on simple measurement of height and weight, can double one’s risk of heart failure, but now, we have gone a step further by using imaging technology to show...

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Bile Acids Trigger Satiety in the Brain

Scientists have discovered a new role for bile acids: they curb appetite by entering the brain. Their findings provide new insights into the signals and mechanisms by which satiety is controlled and may have implications for treating obesity.

Our brain is usually well protected from uncontrolled influx of molecules from the periphery thanks to the blood-brain barrier, a physical seal of cells lining the blood vessel walls. The hypothalamus, however, is a notable exception to this rule. Characterized by “leaky” blood vessels, this region, located at the base of the brain, is exposed to a variety of circulating bioactive molecules. This anatomical feature also determines its function as a rheostat involved in the coordination of energy sensing and feeding behavior.

Several hormone...

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A New Form of Carbon Opens Door to Nanosized Wires

Rakennekuvan yläosassa näkyvät hiiliatomien säännönmukaisesti muodostamat neli-, kuusi- ja kahdeksankulmiot. Alaosa on atomivoimamikroskooppikuva keinotekoisesti valmistetusta materiaalista. Kuva: Marburgin yliopisto, Aalto-yliopisto
Structure of the new network. The upper part schematically shows how the carbon atoms link as squares, hexagons, & octagons. The lower part is an image of the network, obtained with high resolution microscopy. Credit: University Marburg & Aalto University

New type of atomically thin carbon material. Researchers at the University of Marburg in Germany and Aalto University in Finland have now discovered a new carbon network, which is atomically thin like graphene, but is made up of squares, hexagons, and octagons forming an ordered lattice. They confirmed the unique structure of the network using high-resolution scanning probe microscopy and interestingly found that its electronic properties are very different from those of graphene.

In contrast to graphene and other forms of carbon, ...

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An Illuminating Possibility for Stroke Treatment: Nano-Photosynthesis

Brain slices of mice that received nano-photosynthetic therapy (right) have fewer damaged neurons, shown in green, than control mice (left).
Credit: Adapted from Nano Letters 2021, DOI: 10.10.21/acs.nanolett.1c00719

Blocked blood vessels in the brains of stroke patients prevent oxygen-rich blood from getting to cells, causing severe damage. Plants and some microbes produce oxygen through photosynthesis. What if there was a way to make photosynthesis happen in the brains of patients? Now, researchers reporting in ACS’ Nano Letters have done just that in cells and in mice, using blue-green algae and special nanoparticles, in a proof-of-concept demonstration.

Strokes result in the deaths of 5 million people worldwide every year, according to the World Health Organization...

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