Category Health/Medical

Skin and Bones Repaired by Bioprinting During Surgery

schematic showing bioprinting of skin and bone, a rat cartoon with a defect on its head is bioprinted with one bone and 4 skin inks creating bone and skin layers.
Schematic of the skin and bone bioprinting process. After scanning, the bone and then skin layers are bioprinted creating a layered repair with bone, a barrier layer, and dermis and epidermis.
 IMAGE: OZBOLAT LABORATORY, PENN STATE

Fixing traumatic injuries to the skin and bones of the face and skull is difficult because of the many layers of different types of tissues involved, but now, researchers have repaired such defects in a rat model using bioprinting during surgery, and their work may lead to faster and better methods of healing skin and bones.

“This work is clinically significant,” said Ibrahim T. Ozbolat, Hartz Family Career Development Associate Professor of Engineering Science and Mechanics, Biomedical Engineering and Neurosurgery, Penn State...

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Inspired by Nature, the research to develop a new Load-bearing Material

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Fabrication of Cartilage-Inspired Hydrogel/Entangled Polymer–Elastomer Structures Possessing Poro-Elastic Properties

Engineers have developed a new material that mimics human cartilage — the body’s shock absorbing and lubrication system, and it could herald the development of a new generation of lightweight bearings.

Cartilage is a soft fibrous tissue found around joints which provides protection from the compressive loading generated by walking, running or lifting. It also provides a protective, lubricating layer allowing bones to pass over one another in a frictionless way. For years, scientists have been trying to create a synthetic material with the properties of cartilage.

To date, they have had mixed results.

But in a paper published in the journal Applied Polymer Mate...

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Body’s Natural Pain Killers can be enhanced

cookie cutter with pills inside in colorful colors
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A study in cells and mice finds compound works with fewer side effects than opioids. Fentanyl, oxycodone, morphine—these substances are familiar to many as a source of both pain relief and the cause of a painful epidemic of addiction and death.

Scientists have attempted for years to balance the potent pain-relieving properties of opioids with their numerous negative side effects—with mostly mixed results.

Work by John Traynor, Ph.D., and Andrew Alt, Ph.D., and their team at the University of Michigan Edward F. Domino Research Center, funded by the National Institute on Drug Abuse, seeks to side-step these problems by harnessing the body’s own ability to block pain.

All opioid drugs—from poppy-derived opium to heroin—work on receptors that are naturally prese...

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Scientists glimpse signs of a Puzzling State of Matter in a Superconductor

SLAC scientists used an improved X-ray technique to explore exotic states of matter in an unconventional superconductor that conducts electricity with 100% efficiency at relatively high temperatures. They glimpsed the signature of a state known as pair density waves (PDW), and confirmed that it intertwines with another phase known as charge density wave (CDW) stripes – wavelike patterns of higher and lower electron density in the material. CDWs, in turn, are created when spin density waves (SDWs) emerge and intertwine. (Jun-Sik Lee/SLAC National Accelerator Laboratory)

Known as ‘pair-density waves,’ it may be key to understanding how superconductivity can exist at relatively high temperatures...

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