Category Health/Medical

Energy balance includes modulation of dopamine reward signaling. Since the discovery of leptin in the 1990s, researchers have wondered, how does leptin, a hormone made by body fat, suppress appetite? Despite tremendous gains in the intervening three decades, many questions still remain. Now, a new study in mice describes novel neurocircuitry between midbrain structures that control feeding behaviors that are under modulatory control by leptin.

John Krystal, MD, Editor of Biological Psychiatry, said of the findings, “Omrani and colleagues shed light on how, in non-obese animals, leptin puts the brakes on overeating.”

Leptin acts as a critical link between the body and the brain, providing information a...

WEHI researchers have discovered a key differentiation process that provides an essential immune function in helping to control cancer and infectious diseases.

The research, published in Science Immunology, is the first to show a new factor — DC-SCRIPT — is required for the function a particular type of dendritic cell — called cDC1 — that is essential in controlling the immune response to infection.

Led by WEHI Professor Stephen Nutt, Dr Michael Chopin and Mr Shengbo Zhang, it defines the role for a new regulatory protein in producing dendritic cells...

Telehealth has become a critical way for doctors to still provide health care while minimizing in-person contact during COVID-19. But with phone or Zoom appointments, it’s harder for doctors to get important vital signs from a patient, such as their pulse or respiration rate, in real time.

A University of Washington-led team has developed a method that uses the camera on a person’s smartphone or computer to take their pulse and respiration signal from a real-time video of their face...

Researchers are now looking to develop a drug that will boost existing statin drugs to prevent heart disease. The protein that interferes with low-density lipoprotein (LDL) receptors that clear “bad” cholesterol from the blood was identified in findings recently published in Nature Communications by Dawei Zhang, associate professor of pediatrics in the Faculty of Medicine & Dentistry. Excess LDL cholesterol can lead to atherosclerosis — a narrowing and hardening of arteries — and ultimately, heart attack.

“We...