Category Health/Medical

With insights into a molecular pathway that regulates the activity of Tregs, a type of T cell involved in immunosuppression, new research opens up possibly new avenues for treating inflammatory and autoimmune diseases.

Immune response is a balancing act: Too much can lead to inflammatory or autoimmune disease; too little could lead to a serious infection...

People with cancer who exercise generally have a better prognosis than inactive patients. Now, researchers at Karolinska Institutet in Sweden have found a likely explanation of why exercise helps slow down cancer growth in mice: Physical activity changes the metabolism of the immune system’s cytotoxic T cells and thereby improves their ability to attack cancer cells. The study is published in the journal eLife.

“The biology behind the positive effects of exercise can provide new insights into how the body maintains health as well as help us design and improve treatments against cancer,” says Randall Johnson, professor at the Department of Cell and Molecular Biology, Karolinska Institutet, and the study’s corresponding author.

Prior research has shown that physical activity can p...

Hospitalized COVID-19 patients who were taking a daily low-dose aspirin to protect against cardiovascular disease had a significantly lower risk of complications and death compared to those who were not taking aspirin, according to a new study led by researchers at the University of Maryland School of Medicine (UMSOM)...

A metabolite produced following consumption of dietary soy may decrease a key risk factor for dementia — with the help of the right bacteria, according to a new discovery led by researchers at the University of Pittsburgh Graduate School of Public Health.

Their study, published today in the journal Alzheimer’s & Dementia: Translational Research & Clinical Interventions, reports that elderly Japanese men and women who produce equol — a metabolite of dietary soy created by certain types of gut bacteria — display lower levels of white matter lesions within the brain.

“White matter lesions are significant risk factors for cognitive decline, dementia and all-cause mortality,” said lead author Akira Sekikawa, M.D., Ph.D., associate professor of epidemiology at Pitt Public Health...