Category Health/Medical

Trigger that leads to Faster Nerve Healing

New research shows how scientists could foster the biological process that accelerates nerve regeneration.

A new study published in Current Biology identifies the biological triggers that promote quicker nerve regeneration. From their previous studies, the researchers knew that damaged nerves regrow more quickly when “stress granules” in the site of the nerve injury are broken apart. Now they know what causes those stress granules to disassemble through a process called protein phosphorylation.

“The important thing is that we identified the protein that drives that process and showed how that’s regulated,” Jeff Twiss, a UofSC biology professor and co-author on the paper, said.

“It actually opens something new,” Pabitra Sahoo, the paper’s lead author, said...

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Studies offer New Evidence for possible link between Blood Type and COVID-19 susceptibility

Adjusted cumulative incidence plots for mechanical ventilation, CRRT, and ICU discharge. Adjusted cumulative incidence of requiring mechanical ventilation (A) or CRRT (B) during hospital stay by group. (C) Cumulative incidence of being discharged from the ICU by group. Cumulative incidence models were created with death as a competing risk and are adjusted for age, sex, and the presence of ≥1 comorbidity status (binary, yes/no). sHR ratio >1 indicates an increased probability of an event occurring during the study period, whereas a ratio <1 indicates a decreased probability. *Statistically significant P value for a difference between groups.
Adjusted cumulative incidence plots for mechanical ventilation, CRRT, and ICU discharge. Adjusted cumulative incidence of requiring mechanical ventilation (A) or CRRT (B) during hospital stay by group. (C) Cumulative incidence of being discharged from the ICU by group. Cumulative incidence models were created with death as a competing risk and are adjusted for age, sex, and the presence of ≥1 comorbidity status (binary, yes/no). sHR ratio >1 indicates an increased probability of an event occurring during the study period, whereas a ratio <1 indicates a decreased probability. *Statistically significant P value for a difference between groups.

Individuals with blood type O may have lowest risk of infection; individuals with A and AB may have increased risk of severe clinical outcomes...

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Technique to Recover Lost Single-Cell RNA-sequencing Information

Seq-Well resolution example
MIT researchers have greatly boosted the amount of information that can be obtained using Seq-Well, a technique for rapidly sequencing RNA from single cells. This advance should enable scientists to learn much more about the critical genes that are expressed in each cell, and help them to discover subtle differences between healthy and dysfunctional cells for designing new preventions and cures. This image illustrates the improved resolution, right, using the new technique.
Credits:Courtesy of the researchers. Edited by MIT News.

Boosting the efficiency of single-cell RNA-sequencing helps reveal subtle differences between healthy and dysfunctional cells. Sequencing RNA from individual cells can reveal a great deal of information about what those cells are doing in the body...

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Scientists find Neurochemicals have Unexpectedly Profound Roles in the Human Brain

Electrodes for brain research
Virginia Tech researchers with the Fralin Biomedical Research Institute at VTC Center for Human Neuroscience Research construct carbon fiber microelectrodes for real-time detection of dopamine and serotonin activity in human patients. The in-house, custom-made electrodes are narrow and used during deep brain stimulation electrode implantation surgeries to measure activity of both dopamine and serotonin in patients. Shown at right in comparison with a paper clip.

Dopamine, serotonin involved in sub-second perception, cognition...

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