Category Health/Medical

Mild COVID-19 cases can produce strong T cell Response

SARS-CoV-2 , COVID-19
Colorized scanning electron micrograph of a cell (blue) heavily infected with SARS-CoV-2 virus particles (red), isolated from a patient sample. Image captured at the NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland. Credit: NIAID

Mild cases of coronavirus disease 2019 (COVID-19) can trigger robust memory T cell responses, even in the absence of detectable virus-specific antibody responses, researchers report August 14 in the journal Cell. The authors say that memory T cell responses generated by natural exposure to or infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)—the virus that causes COVID-19—may be a significant immune component to prevent recurrent episodes of severe disease.

“We are currently facing the biggest global health emerge...

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The secret of Lymph: How Lymph Nodes help Cancer Cells spread

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The study found that melanoma cells (above) pass through the lymph nodes and pick up a protective coating, allowing them to survive high levels of oxidative stress and go on to form distant tumors.

For decades, physicians have known that many kinds of cancer cells often spread first to lymph nodes before traveling to distant organs through the bloodstream. New research from Children’s Medical Center Research Institute at UT Southwestern (CRI) provides insight into why this occurs, opening up new targets for treatments that could inhibit the spread of cancer.

The study, published today in Nature, found melanoma cells that pass through the lymph nodes pick up a protective coating, allowing them to survive high levels of oxidative stress in the blood and go on to form distant tumors.

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Multivitamin, mineral supplement linked to Less-Severe, Shorter-lasting Illness Symptoms

multivitamins

Older adults who took a daily multivitamin and mineral supplement with zinc and high amounts of vitaminC in a 12-week study experienced sickness for shorter periods and with less severe symptoms than counterparts in a control group receiving a placebo.

The findings by Oregon State University researchers were published in the journal Nutrients.

The research by scientists at OSU’s Linus Pauling Institute involved 42 healthy people ages 55 to 75 and was designed to measure the supplement’s effects on certain immune system indicators. It also looked at bloodstream levels of zinc and vitamins C and D while taking the supplement, as these micronutrients are important for proper immune function.

The immune indicators, including white blood cells’ ability to kill incoming pathogens, ...

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Protein produced by the Nervous System may help Treatments for Inflammatory Diseases

Woman on breathing machine
COPD is the third most common cause of death among inflammatory diseases and allergies the sixth in the United States

A Rutgers-led team may have found the key to treating inflammatory diseases like asthma, allergies, chronic fibrosis and chronic obstructive pulmonary disease (COPD).

In a study published in the journal Nature Immunology, researchers discovered that neuromedin B (NMB), a protein produced by the nervous system, was responsible for preventing overactive immune responses and damaging inflammation. An immune response refers to the body’s ability to recognize and defend itself against harmful substances. Although beneficial to help clear infections, an immune response can also promote damaging inflammation if not properly restricted...

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