Category Health/Medical

Reusable Respirators may be a suitable Alternative to Disposable Respirators

A reusable respirator on a table
credit: NIOSH / CDC
A reusable respirator.

Researchers have found that reusable respirators may be a suitable alternative to disposable N95 respirators currently in high demand. Shortages of respiratory protective devices for healthcare personnel are major concerns during the COVID-19 pandemic. A team of researchers at Baylor College of Medicine, Emory University, the University of Texas Health Science Center at Houston and the National Institute for Occupational Safety and Health Centers at the Centers for Disease Control and Prevention have found that reusable respirators may be a suitable alternative to disposable N95 respirators currently in high demand. The study appears in the journal JAMA.

“Training and fit testing healthcare providers on respirators can be time consuming, a...

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How Trans Fats Assist Cell Death

Trans-Fatty acids facilitate DNA damage-induced apoptosis through the mitochondrial JNK-Sab-ROS positive feedback loop
Authors: Yusuke Hirata, Aya Inoue, Saki Suzuki, Miki Takahashi, Ryo Matsui, Nozomu Kono, Takuya Noguchi, and Atsushi Matsuzawa
Journal: Scientific Reports
DOI: https://doi.org/10.1038/s41598-020-59636-6

Tohoku University researchers in Japan have uncovered a molecular link between some trans fats and a variety of disorders, including cardiovascular and neurodegenerative diseases. Their findings, published in the journal Scientific Reports, implicate their role in enhancing a mitochondrial signalling pathway that leads to programmed cell death.

“Accumulating evidence has associated the consumption of trans-fatty acids with various diseases, including some lifestyle d...

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COVID-19: Stopgap Measure to Treat Respiratory Distress

Researchers from MIT and the University of Colorado at Denver propose using a protein called tissue plasminogen activator, whose structure is shown here, to treat Covid-19 patients in acute respiratory distress.
Image: Wikimedia, MedicineFTWq; edited by MIT News

Researchers at MIT and the University of Colorado at Denver have proposed a stopgap measure that they believe could help Covid-19 patients who are in acute respiratory distress. By repurposing a drug that is now used to treat blood clots, they believe they could help people in cases where a ventilator is not helping, or if a ventilator is not available.

Three hospitals in Massachusetts and Colorado are developing plans to test this approach in severely ill Covid-19 patients...

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Crumpled Graphene makes Ultra-Sensitive Cancer DNA detector

Illinois researchers found that crumpling graphene in DNA sensors made it tens of thousands of times more sensitive, making it a feasible platform for liquid biopsy. Credit: Mohammad Heiranian

Graphene-based biosensors could usher in an era of liquid biopsy, detecting DNA cancer markers circulating in a patient’s blood or serum. But current designs need a lot of DNA. In a new study, crumpling graphene makes it more than ten thousand times more sensitive to DNA by creating electrical “hot spots,” researchers at the University of Illinois at Urbana-Champaign found.

Crumpled graphene could be used in a wide array of biosensing applications for rapid diagnosis, the researchers said. They published their results in the journal Nature Communications.

“This sensor can detect ultra-low...

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