Category Health/Medical

‘Nanoemulsion’ Gels offer new way to Deliver Drugs through the Skin

MIT chemical engineers have devised a way to convert liquid nanoemulsions into solid gels. These gels (red) form almost instantaneously when drops of the liquid emulsion enter warm water.

Novel materials made with FDA-approved components could deliver large payloads of active ingredients. MIT chemical engineers have devised a new way to create very tiny droplets of one liquid suspended within another liquid, known as nanoemulsions. Such emulsions are similar to the mixture that forms when you shake an oil-and-vinegar salad dressing, but with much smaller droplets. Their tiny size allows them to remain stable for relatively long periods of time.

The researchers also found a way to easily convert the liquid nanoemulsions to a gel when they reach body temperature (37 degrees Celsius)...

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Gut Bacteria associated with Chronic Pain for first time

Human gut microbiome composition shows an enormous richness. Each circle represents a bacterial species, while the different colours mark different bacterial phyla. Credit: Dr. Amir Minerbi

People with fibromyalgia show variations in microbiome composition. A research team has shown, for the first time, that there are alterations in the bacteria in the gastrointestinal tracts of people with fibromyalgia. Approximately 20 different species of bacteria were found in either greater or are lesser quantities in the microbiomes of participants suffering from the disease than in the healthy control group.

Fibromyalgia affects 2-4 percent of the population and has no known cure...

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New E-Tattoo Enables Accurate, Uninterrupted Heart Monitoring for Days

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A Chest‐Laminated Ultrathin and Stretchable E‐Tattoo for the Measurement of Electrocardiogram, Seismocardiogram, and Cardiac Time IntervalsAdvanced Science, 2019; 1900290 DOI: 10.1002/advs.201900290

The leading cause of death in Texas is heart disease, according to the National Center for Health Statistics, accounting for more than 45,000 deaths statewide in 2017. A new wearable technology made from stretchy, lightweight material could make heart health monitoring easier and more accurate than existing electrocardiograph machines – a technology that has changed little in almost a century.

Developed by engineers at The University of Texas at Austin and led by Nanshu Lu in the Cockrell School of Engineering, this is the latest incarnation of Lu’s electronic tattoo technology...

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‘Goldilocks’ Neurons promote REM Sleep

Using a technique called optogenetics, a laser light was used to turn off or on MCH neurons time locked with the temperature warming phases. It demonstrated the necessity of the MCH neurons to increase REM sleep during warming toward “just right” room temperature. Picture: Pascal Gugler for Insel Gruppe AG

It has been a mystery why REM sleep, or dream sleep, increases when the room temperature is ‘just right’. Neuroscientists show that melanin-concentrating hormone neurons within the hypothalamus increase REM sleep when the need for body temperature defense is minimized, such as when sleeping in a warm and comfortable room temperature. These data have important implications for the function of REM sleep.

Every night while sleeping, we cycle between two very different states of sleep...

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