Category Health/Medical

Research confirms Gut-brain Connection in Autism

An image showing neurons in the gut of a mouse with the autism-related gene mutation. The study found mice with the mutation had more neurons in the small intestine.
An image showing neurons in the gut of a mouse with the autism-related gene mutation. The study found mice with the mutation had more neurons in the small intestine.

Up to 90% of people with autism suffer from gut problems, but nobody has known why. New research reveals the same gene mutations – found both in the brain and the gut – could be the cause.

The discovery confirms a gut-brain nervous system link in autism, opening a new direction in the search for potential treatments that could ease behavioural issues associated with autism by targeting the gut.

Chief Investigator Associate Professor Elisa Hill-Yardin, RMIT University, said scientists trying to understand autism have long been looking in the brain, but the links with the gut nervous system have only been recently ex...

Read More

Circadian Clocks: Body parts respond to day and night Independently from Brain, studies show

UCI research helps shed new light on circadian clocks
The future implications of our findings are vast,” says Paolo Sassone-Corsi, senior author of one of the two studies on circadian clocks published today in the journal Cell. He directs UCI’s Center for Epigenetics and Metabolism and is a Donald Bren Professor of Biological Chemistry. Penny Lee / UCI School of Medicine

Can your liver sense when you’re staring at a television screen or cellphone late at night? Apparently so, and when such activity is detected, the organ can throw your circadian rhythms out of whack, leaving you more susceptible to health problems.

That’s one of the takeaways from two new studies by University of California, Irvine scientists working in collaboration with the Institute for Research in Biomedicine in Barcelona, Spain.

The studies, published tod...

Read More

How Microbiome is disrupted during IBD: Human Microbiome Project

A chart showing interactions between human and gut microbial features during inflammatory bowel disease.
A depiction of interactions between human and gut microbial features during inflammatory bowel disease.

A new study led by researchers from Harvard T.H. Chan School of Public Health and the Broad Institute of MIT and Harvard is the first to have observed the complex set of chemical and molecular events that disrupt the microbiome and trigger immune responses during flare-ups of inflammatory bowel diseases (IBD), including Crohn’s disease and ulcerative colitis.

While previous studies have cataloged microbial changes during IBD, the researchers in this study developed a unique biotechnology toolbox to understand why microbiomes change during IBD and how this provokes an unhealthy inflammatory reaction...

Read More

Synthetic Version of CBD treats Seizures in Rats

Hemp oil stock art
CBD from extracts of cannabis or hemp plants could be used to treat epilepsy and other conditions. UC Davis chemists have come up with a way to make a synthetic version of CBD and showed that it is as effective as herbal CBD in treating seizures in rats. (Getty images)

A synthetic, non-intoxicating analogue of cannabidiol (CBD) is effective in treating seizures in rats, according to research by chemists at the University of California, Davis.

The synthetic CBD alternative is easier to purify than a plant extract, eliminates the need to use agricultural land for hemp cultivation, and could avoid legal complications with cannabis-related products. The work was recently published in the journal Scientific Reports.

“It’s a much safer drug than CBD, with no abuse potential and doesn...

Read More