Category Health/Medical

Materials are widely used to help heal wounds: Collagen sponges help treat burns and pressure sores, and scaffold-like implants are used to repair bones. However, the process of tissue repair changes over time, so scientists are developing biomaterials that interact with tissues as healing takes place.

Now, Dr Ben Almquist and his team at Imperial College London have created a new molecule that could change the way traditional materials work with the body. Known as traction force-activated payloads (TrAPs), their method lets materials talk to the body’s natural repair systems to drive healing.

The researchers say incorporating TrAPs into existing medical materials c...

New research demonstrates a new optogenetics method that eliminates the need for bulky optical fibers, gives researchers more precise control of the light’s intensity, and allows for stimulating multiple areas of the brain simultaneously. Optogenetics is a biological technique that uses light to turn specific neuron groups in the brain on or off. For example, researchers might use optogenetic stimulation to restore movement in case of paralysis or, in the future, to turn off the areas of the brain or spine that cause pain.

“We’re making these tools to understand how different parts of the brain work,” Gutruf said...

Patients with lung disease could find relief by breathing in messenger RNA molecules. In an advance that could lead to new treatments for lung disease, researchers have now designed an inhalable form of mRNA. This aerosol could be administered directly to the lungs to help treat diseases such as cystic fibrosis, the researchers say.

mRNA, which can induce cells to produce therapeutic proteins, holds great promise for treating a variety of diseases...

A molecule derived from a type of primrose could prove to be a potent inhibitor of metastatic growth for a rare and aggressive cancer. Doctors diagnose about 2000 adults with uveal melanoma, a cancer of the eye, every year. In half of cases, the disease metastasizes to the liver. For these patients treatment options are scarce. Researchers at the Sidney Kimmel Cancer Center (SKCC) — Jefferson Health and the Icahn School of Medicine at Mt. Sinai found that a compound extracted from the Christmas berry primrose plant stops the cancer’s growth in preliminary tests. With further testing, the discovery could lead to new therapeutic options for patients with uveal melanoma.

“I’m very optimistic,” said Jeffrey Benovic, PhD, Thomas Eakins Endowed Profes...