Category Health/Medical

Participant Kelly Thomas, trainer Katie Vogt.
Credit: University of Louisville

Of 4 research participants living with traumatic, motor complete spinal cord injury, 2 are able to walk over ground following epidural stimulation paired with daily locomotor training. In addition, all 4 participants achieved independent standing and trunk stability when using the stimulation and maintaining their mental focus. The study was conducted at the Kentucky Spinal Cord Injury Research Center at the University of Louisville (UofL) and is published in this week’s New England Journal of Medicine. The study was funded by the Leona M. and Harry B. Helmsley Charitable Trust, University of Louisville Hospital and Medtronic plc.

This ground-breaking progress is the newest development in a string of outcomes at ...

Hypothetical updated Jack model of AD biomarkers to include the role of brain vasculature.

Breakdown of blood vessel lining is seen in multiple neurodegenerative diseases. USC scientists say Alzheimer’s could be diagnosed earlier if scientists focus on an early warning within the brain’s circulation system. That’s important because researchers believe that the earlier Alzheimer’s is spotted, the better chance there is to stop or slow the disease.

“Cognitive impairment, and accumulation in the brain of the abnormal proteins amyloid and tau, are what we currently rely upon to diagnose Alzheimer’s disease, but blood-brain barrier breakdown and cerebral blood flow changes can be seen much earlier,” said Berislav Zlokovic, the Mary Hayley and Selim Zilkha Chair in Alzheimer’s Disease Research...

Rectal insulin instillation inhibits inflammation and tumor development in chemically-induced colitis. Journal of Crohn’s and Colitis, 2018; DOI: 10.1093/ecco-jcc/jjy112

Diabetes is not the only disease on which insulin has an effect, it appears. Chronic bowel inflammation can be treated effectively by injecting insulin into the rectum, it appears from a new study, where researchers have tested the treatment on mice. The study is a collaboration between departments at the University of Copenhagen and Roskilde University.

‘Our new treatment with insulin on mice shows great potential against chronic bowel inflammation in humans like Colitis Ulcerosa, which causes a lot of people great discomfort...

This confocal microscopic image shows a two-month-old human esophageal organoid bioengineered by scientists from pluripotent stem cells. About 700 micrometers (0.027 inches) in size, the organoid is stained to visualize key structural proteins expressed in mature esophagus, such as involucrin (green) and cornulin (blue). Researchers report in the journal Cell Stem Cell the organoids enhance the study of esophageal disorders, personalized medical and the development of regenerative tissue therapies for people.
Credit: Cincinnati Children’s

Tiny organoids enable personalized disease diagnosis, regenerative therapies. Scientists working to bioengineer the entire human gastrointestinal system in a laboratory now report using pluripotent stem cells to grow human esophageal organoids.

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