Category Health/Medical

Activated ATF6 Induces Intestinal Dysbiosis and Innate Immune Response to
Promote Colorectal Tumorigenesis

The microbiota in the intestines fuels tumor growth. Scientists have made an unexpected discovery while investigating the triggering factors of colon cancer: Cell stress in combination with an altered microbiota in the colon drives tumor growth. Previously, it was assumed that this combination only contributes to inflammatory intestinal diseases.

“With our study we originally wanted to study the role of bacteria in the intestines in the development of intestinal inflammation,” explains Professor Dirk Haller from the Department of Nutrition and Immunology at the Weihenstephan Science Centre of the TUM...

Their ultrathin, conductive, and transparent hybrid NMs can be applied to the fabrication of skin-attachable NM loudspeakers and voice-recognition microphones, which would be unobtrusive in appearance due to their excellent transparency and conformal contact capability.
Credit: UNIST

An international team, affiliated with UNIST has presented an innovative wearable technology that will turn your skin into a loudspeaker. This breakthrough has been led by Professor Hyunhyub Ko in the School of Energy and Chemical Engineering at UNIST. Created in part to help the hearing and speech impaired, the new technology can be further explored for various potential applications, such as wearable IoT sensors and conformal health care devices.

In the study, the research team has developed ultrathin, transp...

Spraying a multisurface cleaner.
Credit: © Prostock-studio / Fotolia

Commonly used household cleaners could be making children overweight by altering their gut microbiota, suggests a Canadian study published in CMAJ (Canadian Medical Association Journal). The study analyzed the gut flora of 757 infants from the general population at age 3-4 months and weight at ages 1 and 3 years, looking at exposure to disinfectants, detergents and eco-friendly products used in the home.

Researchers from across Canada looked at data from the Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort on microbes in infant fecal matter. They used World Health Organization growth charts for body mass index (BMI) scores...

This is a liver section that shows liver fibrosis revealed by staining of collagen accumulation in a mouse with human like NASH.
Credit: UC San Diego Health

Researchers identify enzyme as responsible for onset and progression of fatty liver disease in mice and human clinical specimens. Researchers at University of California San Diego School of Medicine have discovered using mice and human clinical specimens, that caspase-2, a protein-cleaving enzyme, is a critical driver of non-alcoholic steatohepatitis (NASH), a chronic and aggressive liver condition. By identifying caspase-2’s critical role, they believe an inhibitor of this enzyme could provide an effective way to stop the pathogenic progression that leads to NASH — and possibly even reverse early symptoms.

The findings are published in...