Category Health/Medical

Scientists used CRISPR gene editing to halt the progression of Duchenne muscular dystrophy (DMD) in dogs. The images illustrate dystrophin (in green) in a healthy diaphragm muscle (left), absence of dystrophin in a dog with DMD (center), and restoration of dystrophin in dogs treated with CRISPR (right).
Credit: UT Southwestern

Scientists for the first time have used CRISPR gene editing to halt the progression of Duchenne muscular dystrophy (DMD) in a large mammal, according to a study by UT Southwestern that provides a strong indication that a lifesaving treatment may be in the pipeline...

This graphic illustrates how eating within a 10-hour window protects mice from metabolic disease regardless of whether their bodies have functional circadian clocks.
Credit: Salk Institute

Periods of fasting can protect against obesity and diabetes. Scientists at the Salk Institute found that mice lacking the biological clocks thought to be necessary for a healthy metabolism could still be protected against obesity and metabolic diseases by having their daily access to food restricted to a 10-hour window.

The work, which appeared in the journal Cell Metabolism on August 30, 2018, suggests that the health problems associated with disruptions to animals’ 24-hour rhythms of activity and rest – which in humans is linked to eating for most of the day or doing shift work – can be corrected by eat...

Researchers at the University of Minnesota have fully 3D printed an image sensing array on a hemisphere, which is a first-of-its-kind prototype for a “bionic eye.”
Credit: University of Minnesota, McAlpine Group

A team of researchers at the University of Minnesota have, for the first time, fully 3D printed an array of light receptors on a hemispherical surface. This discovery marks a significant step toward creating a “bionic eye” that could someday help blind people see or sighted people see better.

The research is published today in Advanced Materials, a peer-reviewed scientific journal covering materials science. The author also holds the patent for 3D-printed semiconducting devices...

Newly discovered channels in the skull may provide a shortcut for immune cells going to damaged tissue. Credit: Nahrendorf Lab

Study suggests immune cells rush through channels to get to injured tissue quickly. Bone marrow, the spongy tissue inside most of our bones, produces red blood cells as well as immune cells that help fight off infections and heal injuries. According to a new study of mice and humans, tiny tunnels run from skull bone marrow to the lining of the brain and may provide a direct route for immune cells responding to injuries caused by stroke and other brain disorders. The study was funded in part by the National Institutes of Health and published in Nature Neuroscience.

“We always thought that immune cells from our arms and legs traveled via blood to damaged brain tissue...