Category Health/Medical

Discovery of a new analgesic promises pain relief with fewer downsides

Opioids like morphine are widely used in medical practice due to their powerful pain-relieving effects, yet they carry the risk of serious adverse effects such as respiratory depression and drug dependence. For this reason, Japan has strict regulations in place to ensure that these medications are prescribed only by authorized physicians.

In the United States, the opioid OxyContin was once frequently prescribed, triggering a surge in the misuse of synthetic opioids such as fentanyl. As a result, the number of deaths caused by opioid overdose surpassed 80,000 in 2023, escalating into a national public health crisis now referred to as the “opioid crisis.”

Opioids may soon have a rival, however...

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New AI tool learns to read medical images with far less data

New AI tool learns to read medical images with far less data
GenSeg improves in-domain and out-of-domain generalization performance across a variety of segmentation tasks covering diverse diseases, organs, and imaging modalities. Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-61754-6

A new artificial intelligence (AI) tool could make it much easier—and cheaper—for doctors and researchers to train medical imaging software, even when only a small number of patient scans are available.

The AI tool improves upon a process called medical image segmentation, where every pixel in an image is labeled based on what it represents—cancerous or normal tissue, for example. This process is often performed by a highly trained expert, and deep learning has shown promise in automating this labor-intensive task.

The big challenge is t...

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Sleep disruption damages blood vessels in brain and may increase dementia risk: study

A new study reveals that fragmented sleep causes cellular damage to the brain’s blood vessels, providing further evidence to suggest that sleep disruption predisposes the brain to dementia.

The research, published in the journal Brain, is the first to offer cellular and molecular evidence that sleep disruption directly causes damage to brain blood vessels and blood flow.

“We found that individuals who had more fragmented sleep, such as sleeping restlessly and waking up a lot at night, had a change in their balance of pericytes—a brain blood vessel cell that plays an important role in regulating brain blood flow and the entry and exit of substances between the blood and the brain,” said Andrew Lim, principal investigator of the study and a sleep neurologist and scientist at Sunny...

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This bedtime snack swap could rewire your gut and help prevent diabetes

A small wooden bowl overflowing with pistachios and topped with sprigs of mint
Eating pistachios as a nightly snack for 12 weeks altered which bacteria lived in the digestive system of people with prediabetes, according to a new study by researchers at Penn State. Credit: Jose Calatrava Cano/Getty Images. All Rights Reserved.

Eating pistachios every night for 12 weeks altered bacteria in the gut, according to new study. A new study reveals that swapping a typical nighttime carbohydrate snack for pistachios may beneficially alter gut bacteria in people with prediabetes. Conducted by Penn State researchers, the 12-week clinical trial found that pistachio consumption increased beneficial gut microbes like Roseburia and reduced harmful ones such as Blautia hydrogenotrophica...

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