Category Health/Medical

Chemical compound produces Beneficial Inflammation, Remyelination that could help treat Multiple Sclerosis

Photo shows Hawra Karim (left) and Seema Tiwari-Woodruff. Credit: I. Pittalwala / UC Riverside

Photo shows Hawra Karim (left) and Seema Tiwari-Woodruff. Credit: I. Pittalwala / UC Riverside

Study shows that ‘good inflammation’ promotes axon myelination. Researchers at the University of California, Riverside, now report that indazole chloride, a synthetic compound that acts on one form of the body’s estrogen receptors previously shown to reduce multiple sclerosis symptoms in mouse models, is able to do both: remyelinate (add new myelin to) damaged axons and alter the immune system.

“While additional translational studies are required, indazole chloride and similar drugs may represent a promising new avenue of treating the underlying loss of myelin in multiple sclerosis,” said Seema Tiwari-Woodruff, an associate professor of biomedical sciences in the School of Medicine, who led the m...

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OLEDs become Brighter and more Durable

This is a graphic about improving OLEDS on the nanoscale. Credit Credit: Joan Rafols Ribé (UAB) and Paul Anton Will (TU Dresden)

This is a graphic about improving OLEDS on the nanoscale. Credit Credit: Joan Rafols Ribé (UAB) and Paul Anton Will (TU Dresden)

Researchers demonstrate the possibility of using ultrastable film formation to improve the performance of state-of-the-art OLEDs. The researchers show in a detailed study significant increases of efficiency and operational stability (>15% for both parameters and all cases, significantly higher for individual samples) are achieved for 4 differentultrastable glasses,.
Organic light-emitting diodes (OLEDs) truly have matured enough to allow for first commercial products in form of small and large displays. In order to compete in further markets and even open new possibilities (automotive lighting, head-mounted-displays, micro displays, etc...

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We could Reverse Aging by Removing Wrinkles inside our Cells, study suggests

Irina M. Bochkis, Ph.D., of the University of Virginia School of Medicine, has made a new discovery that could let us prevent or cure diseases such as diabetes and fatty liver disease -- and possibly let us turn back the clock on aging itself. Credit: Dan Addison, University of Virginia Communications

Irina M. Bochkis, Ph.D., of the University of Virginia School of Medicine, has made a new discovery that could let us prevent or cure diseases such as diabetes and fatty liver disease — and possibly let us turn back the clock on aging itself. Credit: Dan Addison, University of Virginia Communications

How would we do it? By using viruses as tiny aestheticians. A new discovery about the effects of aging in our cells could allow doctors to cure or prevent diabetes, fatty liver disease and other metabolic diseases – and possibly even turn back the clock on aging itself. The new finding from the University of Virginia School of Medicine suggests that fatty liver disease and other unwanted effects of aging may be the result of our cells’ nuclei getting wrinkly...

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Lung-on-a-Chip Simulates Pulmonary Fibrosis

The image above shows collagen from a healthy engineered lung tissue. Credit: Ruogang Zhao

The image above shows collagen from a healthy engineered lung tissue. Credit: Ruogang Zhao

New biotech could reduce time and cost of developing medicine for deadly lung disease. The innovation, lung-on-a-chip technology, relies on the same technology used to print electronic chips, photolithography. Only instead of semiconducting materials, researchers placed upon the chip arrays of thin, pliable lab-grown lung tissues – in other words, its lung-on-a-chip technology.

“Obviously it’s not an entire lung, but the technology can mimic the damaging effects of lung fibrosis...

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