Category Health/Medical

AKT isoforms have distinct hippocampal expression and roles in synaptic plasticity. eLife, 2018 DOI: 10.7554/eLife.30640.001

New study sheds light on key protein. For 5 years, the assistant professor of integrative physiology at CU Boulder has been working to better understand a protein called AKT, which is ubiquitous in brain tissue and instrumental in enabling the brain to adapt to new experiences and lay down new memories. Until now, scientists have known very little about what it does in the brain. But in a new paper funded by the National Institutes of Health, Hoeffer and his co-authors spell it out for the first time, showing that AKT comes in 3 distinct varieties residing in different kinds of brain cells and affecting brain health in very distinct ways...

Recombinant protein construction and PNp generation and characterization

Researchers have developed a universal vaccine to combat influenza A viruses that produces long-lasting immunity in mice and protects them against the limitations of seasonal flu vaccines, according to a study led by Georgia State University. The CDC estimates influenza has resulted in between 12,000 and 56,000 deaths annually in the U.S. since 2010.

Seasonal flu vaccines must be updated each year to match the influenza viruses that are predicted to be most common during the upcoming flu season, but protection doesn’t always meet expectations or new viruses emerge and manufacturers incorrectly guess which viruses will end up spreading...

Kiwi fruit, among others, contains a powerful antioxidant shown to halt or prevent fatty liver disease in young mice.

As obesity continues to rise in the U.S., non-alcoholic fatty liver disease (NAFLD) has become a major public health issue, increasingly leading to cancer and liver transplants. But new research from the University of Colorado Anschutz Medical Campus has discovered that a powerful anti-oxidant found in kiwi fruit, parsley, celery and papaya known as pyrroloquinoline quinone, or PQQ, can halt or prevent the progression of fatty liver disease in the offspring of mice fed a high-fat Western-style diet.

Growing evidence suggests that childhood obesity and fatty liver disease is influenced by maternal diet and the infant’s microbiome...

Turmeric powder and roots. Turmeric contains curcumin, which has been shown to have anti-inflammatory and antioxidant properties. Credit: © pinkomelet / Fotolia

Twice-daily supplements boosted cognitive power over 18 months. Daily consumption of a certain form of curcumin improved memory and mood in people with mild, age-related memory loss, according to the results of a study conducted by UCLA researchers. The research, published online Jan. 19 in the American Journal of Geriatric Psychiatry, examined the effects of an easily absorbed curcumin supplement on memory performance in people without dementia, as well as curcumin’s potential impact on the microscopic plaques and tangles in the brains of people with Alzheimer’s disease.

Found in turmeric, curcumin has previously been shown to ha...