Category Health/Medical

Koji Atarashi et al. Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammation, Science (2017). DOI: 10.1126/science.aan4526 Credit: CC0 Public Domain

An international team has found evidence that suggests certain types of oral bacteria may cause or exacerbate bowel disorders. In their paper published in the journal Science, the group describes testing the impact of introducing bacteria found in the mouths of humans to mice models. Xuetao Cao with the Chinese Academy of Medical Sciences offers a Perspective piece on the work done by the team in the same journal issue and suggests that the work might one day lead to the development of new kinds of treatments for common bowel disorders.

Bowel disorders such as irritable bowel syndrome, IBS, ulcerative ...

The system uses a commercial smartphone to acquire and interpret real-time images of an enzymatic amplification reaction that takes place in a silicon microfluidic chip that generates green fluorescence and displays a visual read-out of the test. The system is composed of an unmodified smartphone and a portable 3-D-printed cradle that supports the optical and electrical components, and interfaces with the rear-facing camera of the smartphone. Credit: Micro & Nanotechnology Laboratory, University of Illinois at Urbana-Champaign

A multidisciplinary group that includes the University of Illinois at Urbana-Champaign and the University of Washington at Tacoma has developed a novel platform to diagnose infectious disease at the point-of-care, using a smartphone as the detection instrument in con...

Approximate number of driver mutations needed to cause cancer by area of the body

The results show the number of mutations driving cancer varies considerably across different cancer types. For the first time, scientists have provided unbiased estimates of the number of mutations needed for cancers to develop, in a study of more than 7,500 tumours across 29 cancer types. Researchers from the Wellcome Trust Sanger Institute and their collaborators adapted a technique from the field of evolution to confirm that, on average, one to ten driver mutations are needed for cancer to emerge.

In the future, such approaches could be used in the clinic to identify which few mutations in an individual patient are driving his or her cancer, from amongst the thousands of mutations present...

This is a miniaturized biological solar cell assembled micro-BSC device. Credit: Seokheun Choi

New solar cell could power point-of-care medical devices in limited-resource regions. Researchers at Binghamton University, State University of New York have created a micro-scale biological solar cell that generates a higher power density for longer than any existing cell of its kind. A microfluidic lab-on-a-chip system that generates its own power is essential for stand-alone, independent, self-sustainable point-of-care diagnostic devices to work in limited-resource and remote regions. Miniaturized biological solar cells (or micro-BSCs) can be the most suitable power source for those applications because the technique resembles Earth’s natural ecosystem.

“Micro-BSCs can continuously generate el...