Category Health/Medical

Targeted Treatment could prevent spread of Pancreatic cancer, Heart Damage

Pancreatic cancer cells, under a microscope. Credit: University of Cincinnati

Pancreatic cancer cells, under a microscope. Credit: University of Cincinnati

Researchers at the University of Cincinnati (UC) College of Medicine have shown that a new targeted treatment could benefit patients with certain pancreatic tumors by preventing spread of the cancer and protecting their heart from damage – a direct result of the tumor. Higher levels of serotonin among other tumor secretions can cause injury to the valves of the heart over time, leading to cardiac impairment – a condition referred to as cardiac carcinoid disease – in these patients.

These findings, reported in the November 2017 issue of Molecular Cancer Therapeutics, could lead to another targeted treatment for patients and prevent the onset of additional complications from their cancer...

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Minimally Invasive Treatment provides Relief from Back Pain

Lumbar spine MRI showing vertebra at baseline and three months after treatment. Credit: Radiological Society of North America

Lumbar spine MRI showing vertebra at baseline and three months after treatment. Credit: Radiological Society of North America

The majority of patients were pain free after receiving a new image-guided pulsed radiofrequency treatment for low back pain and sciatica, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA). Low back pain is an extremely common problem that affects at least 80% of the population at some point in their lifetime. It is the most common cause of job-related disability. Low back pain affects men and women equally.

Most back pain is short-term, but about 20% of people affected by acute low back pain go on to develop chronic low back pain lasting a year or more...

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Cardiovascular disease: The Immune response to Heart Attacks

Clusters of B (red) and T (green) lymphocytes in pericardial adipose tissue. Fat-laden cells and connective tissue are stained blue. (Mariaelvy Bianchini; Michael Horckmans/LMU)

Clusters of B (red) and T (green) lymphocytes in pericardial adipose tissue. Fat-laden cells and connective tissue are stained blue. (Mariaelvy Bianchini; Michael Horckmans/LMU)

The damage caused by a heart attack triggers an inflammatory reaction which degrades the affected tissue. This response is orchestrated by immune cells that reside in the nearby pericardial adipose tissue, as a study by a team of Ludwig-Maximilians-Universitaet (LMU) in Munich shows. Following a heart attack, the innate immune system must kick in fast in order to limit the damage and stimulate tissue repair...

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Trigger for most common form of Vision Loss discovered

Trigger for most common form of vision loss discovered

Jayakrishna Ambati, M.D., (left) and Nagaraj Kerur, Ph.D., have discovered a crucial trigger for macular degeneration, a condition which robs millions of their sight. The discovery may allow doctors to intervene early to halt the process. Credit: Josh Barney | UVA Health System

Unexpected finding points to potential way to stop macular degeneration. Researchers at the University of Virginia School of Medicine have discovered a critical trigger for the damaging inflammation that ultimately robs millions of their sight. The finding may allow doctors to halt the inflammation early on, potentially saving patients from blindness. “Almost 200 million people in the world have macular degeneration...

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