Category Health/Medical

GF male mice display dysregulated network of miRNA expression in the amygdala and PFC. a Schematic representation of experimental design. b Donut plot representing the number of increased and decreased miRNA in the amygdala (outer plot) and PFC (inner plot) when comparing CON vs GF mice. c Volcano plot representing fold change against significance (P < 0.05) between CON and GF mice in the amygdala and PFC. d Venn diagram reporting overlapping differentially regulated miRNA between all three experimental groups in the amygdala representing the effect of colonization of GF mice on miRNAs. e Represents the impact of colonization of GF mice in the PFC. f Number of miRNAs by name that are normalized by colonization and common in both brain regions...

NAFLD patients have augmented plasma DPP4 activity.
•Hepatocyte-specific DPP4 overexpression in mice.
(1) promotes fatty liver disease.
(2) induces hepatic insulin resistance.
(3) reduces systemic levels of active GLP-1.
(4) enhances adipose tissue expansion and inflammation.

HDL cholesterol and risk of all-cause mortality in the general population. Based on 52 268 men and 64 240 women from the Copenhagen General Population Study and the Copenhagen City Heart Study combined. Hazard ratio (solid line) and 95% confidence interval (dashed lines) from age and study adjusted Cox regression using restricted cubic splines. The concentration of HDL cholesterol associated with lowest mortality was used as reference. The light blue area indicates the distribution of HDL cholesterol concentrations in men and women. CI, confidence interval; HDL, high-density lipoprotein.

Protein secondary structure analysis of dried blood serum using infrared spectroscopy to identify markers for colitis screening. Journal of Biophotonics, 2017; e201700057 DOI: 10.1002/jbio.201700057