Category Health/Medical

Scan of a heart.
Credit: The University of Manchester

Pioneering study is set to help surgeons repair hearts without damaging precious tissue. A team of scientists from Liverpool John Moores University (LJMU), The University of Manchester, Aarhus University and Newcastle University, have developed a way of producing 3D data to show the cardiac conduction system in unprecedented detail.

The new data in this study gives them a much more accurate framework than previously available for computer models of the heartbeat and should improve our ability to make sense of troublesome heart rhythms like atrial fibrillation that affects 1.4 million people in the UK. The data reveals exactly where the cardiac conduction system is in a normal heart...

Mice fed Tryptophan develop Immune cells that foster a tolerant gut. Immune cells patrol the gut to ensure that harmful microbes hidden in the food we eat don’t sneak into the body. Cells that are capable of triggering inflammation are balanced by cells that promote tolerance, protecting the body without damaging sensitive tissues. When the balance tilts too far toward inflammation, inflammatory bowel disease can result.

Now, researchers at Washington University School of Medicine in St. Louis have found that a kind of tolerance-promoting immune cell appears in mice that carry a specific bacterium in their guts...

Researchers at Washington University School of Medicine in St. Louis have found that a particular gut microbe can prevent severe flu infections in mice, likely by breaking down naturally occurring compounds — called flavonoids — commonly found in foods such as black tea, red wine and blueberries. Credit: © taa22 / Fotolia

Natural Compound Coupled with Specific Gut Microbes may Prevent Severe Flu

A particular gut microbe can prevent severe flu infections in mice, likely by breaking down naturally occurring compounds – called flavonoids – commonly found in foods such as black tea, red wine and blueberries. The research in mice by scientists at Washington University School of Medicine in St...

Highlights
•Diurnal changes in hypothalamic TCPTP coordinate feeding with energy expenditure
•Feeding represses hypothalamic TCPTP to increase energy expenditure
•TCPTP inhibits insulin signaling in AgRP neurons to repress energy expenditure
•Insulin signaling in AgRP neurons increases the browning of white fat

Scientists at Monash University’s Biomedicine Discovery Institute have found a mechanism by which the brain coordinates feeding with energy expenditure, solving a puzzle that has previously eluded researchers and offering a potential novel target for the treatment of obesity. Obesity – a major risk factor for many diseases including cardiovascular disease, Type 2 diabetes, liver disease and several cancers – is at epidemic levels in Australia.

Researchers from the Metabolic D...