Category Health/Medical

Vitamin C and Doxycycline combination therapy for fighting Cancer

Cancer stem cells, which fuel the growth of fatal tumours, can be knocked out by a one-two combination of antibiotics and Vitamin C in a new experimental strategy, published by researchers at the University of Salford, UK. The antibiotic, Doxycycline, followed by doses of ascorbic acid (Vitamin C), were surprisingly effective in killing the cancer stem cells under laboratory conditions, according to the research published in the journal Oncotarget.

The researchers say their method offers a new explanation for how to prevent cancer cells from becoming treatment-resistant and how combinations therapies can be developed to overcome drug resistance. Prof...

Direct 3D cell-printing of human skin with functional transwell system. Biofabrication, 2017; 9 (2): 025034 DOI: 10.1088/1758-5090/aa71c8

Scientists in South Korea have come up with a new method for 3D printing human skin, which both shortens the process and reduces the cost. Reporting their results today in the journal Biofabrication, the team from Pohang University of Science and Technology demonstrate a new 3D cell printing strategy, for engineering a 3D human skin model in a single step process...

Immunologic history of type 1 diabetes.

Data presented at American Diabetes Association meeting describes a potential new mechanism by which the BCG vaccine may restore the proper immune response to the insulin-secreting islet cells of the pancreas. Presented by Denise Faustman, MD, PhD, director of the Massachusetts General Hospital Immunobiology Laboratory and principal investigator of the trial, the findings suggest that BCG may induce a permanent increase in expression of genes that restore the beneficial regulatory T cells (Tregs) that prevent the immune system from attacking the body’s own tissue.

“Many groups are looking at the ability of BCG vaccination to reverse autoimmunity,” says Faustman, who is an associate professor of Medicine at Harvard Medical School...