Category Health/Medical

High-Fat Diet in Pregnancy can cause Mental Health Problems in Offspring

Figure 8. (A) The location of area 10 of the prefrontal cortex (PFC) was determined using figures from Paxinos Stereotaxic Atlas (39). DAPI staining was used to differentiate the layers of the cortex, numbered 1–6. (B) Representative images of the differences seen in 5-HT fiber innervation of medial area 10 of the PFC between the four diet groups. (C) Exposure to a postweaning high-fat diet (HFD) decreased mean intensity of 5-HT immunoreactive signal in layer 1 of medial area 10 in the PFC (F1,16 = 7.662, p = 0.014). (D) 5-HT immunoreactivity in the same region was further affected by an interaction between gender and postweaning diet (F1,16 = 7.497, p = 0.015), with mean intensity decreased in postweaning HFD males compared to control males (F1,16 = 13.895, p = 0.002). Data shown as mean ± SEM. # denotes a postweaning diet effect, p < 0.05. Scale bars are 400 µm. Sample sizes for the 5-HT immunohistochemisty are as follows: CTR/CTR n = 6 (n = 2 males; n = 4 females), CTR/HFD n = 6 (n = 3 males; n = 3 females), HFD/CTR n = 6 (n = 3 males; n = 3 females), and HFD/HFD n = 6 (n = 3 males; n = 3 females).

(A) The location of area 10 of the prefrontal cortex (PFC) was determined using figures from Paxinos Stereotaxic Atlas (39). DAPI staining was used to differentiate the layers of the cortex, numbered 1–6. (B) Representative images of the differences seen in 5-HT fiber innervation of medial area 10 of the PFC between the four diet groups. (C) Exposure to a postweaning high-fat diet (HFD) decreased mean intensity of 5-HT immunoreactive signal in layer 1 of medial area 10 in the PFC (F1,16 = 7.662, p = 0.014). (D) 5-HT immunoreactivity in the same region was further affected by an interaction between gender and postweaning diet (F1,16 = 7.497, p = 0.015), with mean intensity decreased in postweaning HFD males compared to control males (F1,16 = 13.895, p = 0.002). Data shown as mean ± SEM...

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Laser Rx Reduces Eye Floaters

Subjective vs Objective Grading of Floater Resolution at 6 Months Using a 5-Level Qualitative Scale

Subjective vs Objective Grading of Floater Resolution at 6 Months Using a 5-Level Qualitative Scale

Patients reported improvement in symptoms of eye floaters after treatment with a laser, according to a study published by JAMA Ophthalmology. Floaters become more prevalent with age and although most patients grow accustomed to them, many find them bothersome, and they can worsen visual quality. Three management options exist for floaters: patient education and observation; surgery; and the laser procedure, YAG vitreolysis, of which there are limited published studies on its effectiveness for treating floaters.

Chirag P. Shah, M.D., M.P.H., and Jeffrey S. Heier, M.D...

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Why Sugary Drinks and Protein-Rich Meals don’t go well Together

Shanon L. Casperson, Clint Hall, James N. Roemmich. Postprandial energy metabolism and substrate oxidation in response to the inclusion of a sugar- or non-nutritive sweetened beverage with meals differing in protein content. BMC Nutrition, 2017; 3 (1) DOI: 10.1186/s40795-017-0170-2

Shanon L. Casperson, Clint Hall, James N. Roemmich. Postprandial energy metabolism and substrate oxidation in response to the inclusion of a sugar- or non-nutritive sweetened beverage with meals differing in protein content. BMC Nutrition, 2017; 3 (1) DOI: 10.1186/s40795-017-0170-2

Having a sugar-sweetened drink with a high-protein meal may negatively affect energy balance, alter food preferences and cause the body to store more fat, according to a study published in the open access journal BMC Nutrition...

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How Physical Exercise Prevents Dementia

Numerous studies have shown that physical exercise seems beneficial in the prevention of cognitive impairment and dementia in old age. Gerontologists and sports physicians at Goethe University Frankfurt have examined the effects of regular exercise on brain metabolism and memory of 60 participants aged between 65 and 85 in a randomised controlled trial. Their conclusion: regular physical exercise not only enhances fitness but also has a positive impact on brain metabolism.

As the researchers report in the current issue of the medical journal Translational Psychiatry, they thoroughly examined all the participants in the SMART study (Sport an...

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