Category Health/Medical

Patients’ own Fat Tissue can help treat Joint problems

Lipogems® is a non-expanded and microfragmented adipose tissue graft that is injected into damaged areas of the body in order to provide a cushion and structural support while promoting a healing environment. Lipogems® preserve the natural healing properties of adipose tissue by maintaining the fats Vascular Stromal Niches which contain mesenchymal cells and pericytes. The objective of the Lipogems® product is to favor the natural regenerative process of tissues and it is used in numerous pathologies.

Lipogems® is a non-expanded and microfragmented adipose tissue graft that is injected into damaged areas of the body in order to provide a cushion and structural support while promoting a healing environment. Lipogems® preserve the natural healing properties of adipose tissue by maintaining the fats Vascular Stromal Niches which contain mesenchymal cells and pericytes.

Body fat now can help treat bone joint conditions, including injuries and osteoarthritis – the type of arthritis caused by wear and tear in tissue between joints, which affects 27 million people. A new device gently suctions, processes and uses a patient’s own fat tissue to provide a potential source of stem cells and growth factors to promote healing...

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Self-Ventilating Workout Suit keeps Athletes Cool and Dry

Self-Ventilating Workout Suit keeps Athletes Cool and Dry

Self-Ventilating Workout Suit keeps Athletes Cool and Dry

Ventilating flaps lined with live cells open and close in response to an athlete’s sweat. MIT team has designed a breathable workout suit with ventilating flaps that open and close in response to an athlete’s body heat and sweat. These flaps, which range from thumbnail- to finger-sized, are lined with live microbial cells that shrink and expand in response to changes in humidity. The cells act as tiny sensors and actuators, driving the flaps to open when an athlete works up a sweat, and pulling them closed when the body has cooled.

They have also fashioned a running shoe with an inner layer of similar cell-lined flaps to air out and wick away moisture...

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Tau Prevents Synaptic Transmission at Early stage of Neurodegeneration

Interfering with Tau N-terminal-dependent vesicle-binding reverts Tau-induced presynaptic deficits in fly neurons.

Interfering with Tau N-terminal-dependent vesicle-binding reverts Tau-induced presynaptic deficits in fly neurons. Drosophila larvae used in (a–c) express UAS-TauΔN (R406W, V337M or P301L) under the D42-Gal4 motor neuron driver. (a) FRAP measurements of vesicle mobility within synaptic boutons. Fluoresence recovery (% of initial fluorescence) was plotted over time and fit with double-exponential curves. n=22 (R406W), 20 (ΔN_R406W, ΔN_V337M), 24 (ΔN_P301L) or 25 (Control) boutons (3–5 boutons per animal). (b) Synapto-pHluorin responses to stimulation at 10 Hz with the presence of bafilomycin. Fluorescence change ΔF at ratio to maximal ΔF (NH4Cl dequenching) was plotted over time during the stimulation. Two-way ANOVA, n=7 (R406W, ΔN_R406W, ΔN_V337M, ΔN_P301L),9 (Control) NMJs (animals)...

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New Hope for Slow-Healing Wounds

Efficient miR-92a downregulation in the skin upon treatment with caged antimiR-92a.

Efficient miR-92a downregulation in the skin upon treatment with caged antimiR-92a.

MicroRNAs are interesting target structures for new therapeutic agents. They can be blocked through synthetic antimiRs. However, to date it was not possible to use these only locally. Researchers at Goethe University Frankfurt have now successfully achieved this in the treatment of impaired wound healing with the help of light-inducible antimiRs.

MicroRNAs are small gene fragments which bond onto target structures in cells and in this way prevent certain proteins from forming. As they play a key role in the occurrence and manifestation of various diseases, researchers have developed what are known as antimiRs, which block microRNA function...

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