Category Health/Medical

At left, head and neck squamous cell carcinoma invasive growth, and at right, cancer stem cells (shown in red) in head and neck squamous cell carcinoma. Credit: Demeng Chen and Cun-Yu Wang/UCLA

Head and neck squamous cell carcinoma is a highly invasive form of cancer and frequently spreads to the cervical lymph nodes. Currently, cisplatin is the standard therapeutic drug used for people with HNSCC. Yet, more than 50% of people who take cisplatin demonstrate resistance to the drug, and they experience a recurrence of the cancer. The 5-year survival rates remain sorely low and researchers still don’t understand the underlying mechanisms behind head and neck squamous carcinoma.

Cancer stem cells are known to be responsible for tumor formation and development; they also self-renew and tend to ...

Scientists at Los Alamos National Laboratory and their research partners are creating innovative 2-D layered hybrid perovskites that allow greater freedom in designing and fabricating efficient optoelectronic devices. Credit: Los Alamos National Laboratory

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating innovative 2D layered hybrid perovskites that allow greater freedom in designing and fabricating efficient optoelectronic devices...

ab115630 at 10ug/ml staining GRASP1 in Human brain (cortex) tissue by immunohistochemistry (FFPE)

Learning and memory depend on cells’ ability to strengthen and weaken circuits in the brain. Now, researchers at Johns Hopkins Medicine report that a protein involved in recycling other cell proteins plays an important role in this process. Removing this protein reduced mice’s ability to learn and recall information. “We see deficits in learning tasks,” says Richard Huganir, Ph.D., professor and director of the neuroscience department at the Johns Hopkins University School of Medicine.

The team also found mutations in the gene that produces the recycling protein in a few patients with intellectual disability, and those genetic errors affected neural connections when introduced into mouse brain...

Researchers at Johns Hopkins University found a link between rapid drops in blood pressure, known as orthostatic hypotension, and an increased risk of dementia. Photo by ronstik/Shutterstock

Middle-aged people who experience temporary blood pressure drops that often cause dizziness upon standing up may be at an increased risk of developing cognitive decline and dementia 20 years later, new Johns Hopkins Bloomberg School of Public Health research suggests. The findings suggest that these temporary episodes – orthostatic hypotension – may cause lasting damage, possibly because they reduce needed blood flow to the brain...