Category Health/Medical

An engineering team at Washington University in St. Louis says a compound found in green tea may be of particular benefit to patients struggling with multiple myeloma and amyloidosis. Aggregation of Full Length Immunoglobulin Light Chains from AL Amyloidosis Patients Is Remodeled by Epigallocatechin-3-gallate. Journal of Biological Chemistry, 2016; jbc.M116.750323 DOI: 10.1074/jbc.M116.750323

Epigallocatechine-3-gallate (EGCG), a polyphenol found in green tea leaves, may be of particular benefit to patients struggling with multiple myeloma and amyloidosis. These patients are susceptible to a frequently fatal condition called light chain amyloidosis, in which parts of the body’s own antibodies become misshapen and can accumulate in various organs, including the heart and kidneys...

Loss of IL-27 signaling results in increased disease severity and lung immunopathology after SeV.

Respiratory syncytial virus (RSV) causes ~60,000 hospitalizations of children aged 0 to four, and nearly 200,000 hospitalizations and 14,000 deaths among adults 65 and older. However, there are virtually no vaccines or treatments for these infections. Perelman School of Medicine at the University of Pennsylvania and the University of Pennsylvania School of Veterinary Medicine found evidence that cytokine Interleukin 27 (IL-27), may be the key to fighting and treating these infections.

Working with a mouse-model of parainfluenza virus infection, Sendai virus, which causes similar symptoms and patterns of tissue damage to RSV, researchers found that mice fared much worse in fighting the infectio...

Maternal licorice consumption during pregnancy and pubertal, cognitive and psychiatric outcomes in children. American Journal of Epidemiology, 2017

Liquorice and its natural sweetener, glycyrrhizin, can have long-term harmful effects on the development of the fetus. A new Finnish study supports food recommendations for families with children in that women should avoid consuming large amounts of liquorice during pregnancy. The limit for safe consumption is not known. In the study, youths exposed to large amounts of liquorice in the womb performed less well than others in cognitive reasoning tests by a psychologist. The difference was equivalent to approximately 7IQ points...

Zircones. Credit: Anders Lindskog

Sustained meteorite bombardment. Some 470 million years ago, during the middle part of the geological period known as the Ordovician, an asteroid collision took place somewhere between Mars and Jupiter. The collision caused an explosion that sent a cascade of meteorites towards Earth. The heavy bombardment of Earth continued for millions of years, and even today some 20% of all meteorites that reach Earth originate from this asteroid break-up. At the same time Earth witnessed the greatest rise in marine biodiversity since the origin of multicellular life...