Category Health/Medical

High expression of PHLDB3 is found in multiple cancers and mutually exclusive to TP53 mutations in some cancers.

Tulane University researchers have discovered that the protein PHLDB3, thought to be a potential tumor suppressor, actually allows cancer cells to thrive in pancreatic, prostate, colon, breast, lung, and other common cancers. The discovery could explain how cancer is able to overcome p53 – a key tumor-suppressing protein. The findings, recently published in Nature Communications, could eventually lead to targeted diagnostic tests and treatments of certain types of cancer.

“Now that we’ve identified the molecule, we could utilize it as an anti-cancer target,” said Dr. Hua Lu, the Reynolds and Ryan Families Chair in Translation Cancer at Tulane...

Bioprinter prototype. Credit: Image courtesy of Universidad Carlos III de Madrid – Oficina de Información Científica

Scientists from Universidad Carlos III de Madrid (UC3M), CIEMAT Hospital General Universitario Gregorio Marañón, with the firm BioDan Group, have a prototype for a 3D bioprinter that can create functional human skin. This skin is adequate for transplanting to patients or for use in research or the testing of cosmetic, chemical, and pharmaceutical products.

This new human skin is one of the first living human organs created using bioprinting to be introduced to the marketplace...

NTU researcher Lee Jia Min working on 3D bioprinting of blood vessels. Credit: Image courtesy of Nanyang Technological University

Tissue implants customized to a patient could soon be printed using a new type of 3D-printer under development by Nanyang Technological University, Singapore (NTU Singapore) and a Singapore-based 3D printing start-up focused on healthcare. This new printer can print the supporting structure layer by layer and insert living cells to form a live tissue that could aid in regeneration of particular tissues or organs. The industry research tie-up is one of the many partnerships made possible by the National Additive Manufacturing Innovation Cluster, also known as NAMIC.

Since the formation of NAMIC by the National Research Foundation (NRF) Singapore and SPRING Singap...

The “Mama-Ope” (Mother’s Hope) kit, invented by Ugandan engineers, is a biomedical smart jacket and a mobile phone app that diagnoses pneumonia faster than a doctor (AFP Photo/ISAAC KASAMANI)

A team of Ugandan engineers has invented a “smart jacket” that diagnoses pneumonia faster than a doctor, offering hope against a disease which kills more children worldwide than any other. The idea came to Olivia Koburongo, 26, after her grandmother fell ill, and was moved from hospital to hospital before being properly diagnosed with pneumonia. “It was now too late to save her,” said Koburongo. “It was too hard to keep track of her vitals, of how she’s doing, and that is how I thought of a way to automate the whole process and keep track of her health.”

Koburongo took her idea to fellow telecommunic...