
Eosinophil recruitment into tumour tissue is induced by IL-33 expression (C57BL/6 mouse).
UBC researchers have discovered how cancer cells become invisible to the body’s immune system, a crucial step that allows tumours to metastasize. “The immune system is efficient at identifying and halting the emergence and spread of primary tumours but when metastatic tumours appear, the immune system is no longer able to recognize the cancer cells and stop them,” said Wilfred Jefferies, Michael Smith Laboratories and a professor of Medical Genetics and Microbiology and Immunology at UBC.
“We discovered a new mechanism that explains how metastatic tumours can outsmart the immune system and we have begun to reverse this process so tumours are revealed to the immune system once again.”
Cancer cells gene...
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