Category Health/Medical

CRISPR gene editing reveals new therapeutic approach for blood disorders. Credit: St. Jude Children’s Research Hospital

An international team has found a way to use CRISPR gene editing to help fix sickle cell disease and beta-thalassemia in blood cells isolated from patients. The study in Nature Medicine, provides proof-of-principle for a new approach to treat common blood disorders by genome editing.

“Our approach to gene editing is informed by the known benefits of hereditary persistence of fetal hemoglobin,” said Mitchell J. Weiss, M.D., Ph.D., chair of the St. Jude Department of Hematology...

The legions of nanorobotic agents are actually composed of more than 100 million flagellated bacteria — and therefore self-propelled — and loaded with drugs that moved by taking the most direct path between the drug’s injection point and the area of the body to cure. Credit: Montréal Nanorobotics Laboratory

Researchers have just achieved a spectacular breakthrough in cancer research. They have developed new nanorobotic agents capable of navigating through the bloodstream to administer a drug with precision by specifically targeting the active cancerous cells of tumours. This way of injecting medication ensures the optimal targeting of a tumour and avoids jeopardizing the integrity of organs and surrounding healthy tissues...

The tip of an atomic force microscope on a cantilevered arm is used to pull a graphene nanoribbon the same way it would be used to pull apart a protein or a strand of DNA in a Rice University lab. The microscope can be used to measure properties like rigidity in a material as it’s manipulated by the tip. Courtesy of the Kiang Research Group

Graphene nanoribbons (GNRs) bend and twist easily in solution, making them adaptable for biological uses like DNA analysis, drug delivery and biomimetic applications, according to scientists at Rice University. GNR’s can be thousands of times longer than they are wide. They can be produced in bulk by chemically “unzipping” carbon nanotubes, a process invented by Rice chemist and co-author James Tour and his lab.

Their size means they can operate on th...

A schematic diagram of the SWCNT electrical immunosensor with two pairs of concentration and detection electrodes.

An electrical immunosensor has been developed to detect acute myocardial infarction within a minute. The system works by measuring the level of cardiac troponin I (cTnI), a protein that is excreted by the heart muscle into the blood following a heart attack. Prof. Jang states, “This new immunosensor is constructed in a different way than any other sensor.” He adds, “Owing to the new design of this immunosensor, this device is able to rapidly diagnose the level of heart attacks at the point of care.”

It is a a rapid, label-free, and highly sensitive single-walled carbon nanotube (SWCNT) electrical immunosensor, featuring two pairs of electrodes...