Category Health/Medical

Foundational Technology to Make Cancer Cells Revert to Normal Cells?

Schematic diagram of the research results. Professor Kwang-Hyun Cho’s research team developed a source technology to systematically discover key control factors that can induce reversibility of colon cancer cells through a systems biology approach and a digital twin simulation analysis of the differentiation trajectory of normal colon cells, and verified the effects of reversion on actual colon cancer through molecular cell experiments and animal experiments. 

A research team has developed a groundbreaking technology that can treat colon cancer by converting cancer cells into a state resembling normal colon cells without killing them, thus avoiding side effects.

Despite the development of numerous cancer treatment technologies, the common goal of current cancer therapies is to elim...

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Can the Heart Heal itself? New study says it can

A doctor examines a patient wearing a pink robe sitting on the edge of a bed
Tissue from patients with artificial hearts, or left ventricular assist devices, regenerated muscle cells at more than six times the rate of healthy hearts, according to a paper published in the journal Circulation.
Photo by Halfpoint Images via Getty Images

An international research team found evidence that heart muscle can regenerate after heart failure in some people with artificial hearts. A research team co-led by a physician-scientist at the University of Arizona College of Medicine — Tucson’s Sarver Heart Center found that a subset of artificial heart patients can regenerate heart muscle, which may open the door to new ways to treat and perhaps someday cure heart failure. The results were published in the journal Circulation.

According to the Centers for Disease Control and Pr...

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Introducing Perceptein, a Protein-based Artificial Neural Network in Living Cells

Here, each neuron is represented as spacecrafts, with their pilots in the cockpits depicted in the shape of protein 3D structures. These spacecrafts collectively process and transmit information to the final red neuron to make decisions on space navigation. The wires that connect the neurons, with the green substance inside, indicate the flow of biological information. Credit: Ehmad Chehre

Westlake University in China and the California Institute of Technology have designed a protein-based system inside living cells that can process multiple signals and make decisions based on them.

The researchers have also introduced a unique term, “perceptein,” as a combination of protein and perceptron...

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New Gene Therapy could Alleviate Chronic Pain, Researchers find

Researchers create gene therapy with potential to treat peripheral pain conditions
Credit: Cell (2024). DOI: 10.1016/j.cell.2024.11.001

Pain is meant to be a defense mechanism. It creates a strong sensation to get us to respond to a stimulus and prevent ourselves from further harm. But, sometimes injuries, nerve damage, or infections can cause long-lasting, severe bouts of pain that can make daily life unbearable.

What if there was a way to simply turn off pain receptors? UNC School of Medicine researchers Bryan L. Roth, MD, Ph.D., the Michael Hooker Distinguished Professor of Pharmacology, and Grégory Scherrer, PharmD, Ph.D., associate professor of cell biology and physiology and the UNC Neuroscience Center, have just proven that it is possible.

Using a tool designed by Roth in the early 2000s, the labs have created a new system that reduces acute and tissu...

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