Category Health/Medical

Electron’s 1D Metallic Surface State observed

In 1-D, electrons cannot "pass each other". Credit: Osaka University

In 1-D, electrons cannot “pass each other”. Credit: Osaka University

A step for prediction of electronic properties of extremely-fine metal nanowires in next-generation semiconductors. In 1D, various exotic phenomena are predicted that are totally different from those in the 3D world in which we live. One of the reasons of this is that particles cannot pass each other in 1D.

Researchers in Japan and France artificially created such unique 1D nano electronic systems on the surface of a solid, and observed the 1D electronic state (energy and kinetic momentum of electrons) by analyzing photo-emitted electrons from the sample, and verified the electronic structure...

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Mesh-like Scaffold is Disordered in Alzheimer’s-affected cells

A cell nucleus from a normal, healthy brain is shown at left. The lamin nucleoskeleton forms the perimeter around the nucleus. By contrast, tunnel-like anomalies are evident in the nucleus of the Alzheimer's disease-affected cell shown at right. This image is from the laboratory of Bess Frost, Ph.D., of the School of Medicine and Barshop Institute for Longevity and Aging Studies at The University of Texas Health Science Center at San Antonio. Credit: Laboratory of Bess Frost, Ph.D./UT Health Science Center San Antonio

A cell nucleus from a normal, healthy brain is shown at left. The lamin nucleoskeleton forms the perimeter around the nucleus. By contrast, tunnel-like anomalies are evident in the nucleus of the Alzheimer’s disease-affected cell shown at right. This image is from the laboratory of Bess Frost, Ph.D., of the School of Medicine and Barshop Institute for Longevity and Aging Studies at The University of Texas Health Science Center at San Antonio. Credit: Laboratory of Bess Frost, Ph.D./UT Health Science Center San Antonio

A new finding offers a insight into one of the earliest biological events of Alzheimer’s disease and is expected to open new avenues of study. Neuronal cell death in Alzheimer’s disease is linked to disruption of a lamin nucleoskeleton that surrounds the nucleus of the cells...

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Proteomics and Precision Medicine

Proteomics and precision medicine

This retinal scan of a uveitis patient demonstrates retinal thickening (red) involving the central retina resulting in compromising vision. University of Iowa researchers recently recently used proteomics (protein profiling) to devise a successful treatment strategy for a patient with uveitis, a disease which can have many causes, making it particularly difficult to diagnose and treat effectively. Credit: Vinit Mahajan, University of Iowa Health Care

Protein analysis can make diagnoses more accurate and treatments better targeted to individual patients. Researchers have used personalized proteomics to devise a successful treatment for a patient with uveitis, a potentially blinding eye disease that can have many causes, making it particularly difficult to diagnose and treat effectively.

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Hair thinning by stem cell loss

Why people lose their locks in old age may be related to the aging of hair follicle stem cells, two new studies suggest. Though it is known that mammals that live for longer lifespans lose their hair, the mechanisms underlying this fate have been a mystery. Hair follicle stem cells (HFSCs), which generate the sacs or follicles that produce hair, keep hair growth going repeatedly over time.

Surprisingly, they have even been shown, in mice experiments, to resist aging. To better understand the role HFSCs might play in aging-associated hair loss, Hiroyuki Matsumura and colleagues studied hair follicles in a mouse model of accelerated hair loss...

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