
MCP-1 released by smooth muscle and endothelial cells promotes the recruitment of monocytes and macrophages to the subendothelial cell layer. Deposition of lipids within these monocytes and macrophages then leads to development of atherosclerotic lesions.
This is one of the 1st studies to demonstrate the effect of red blood cells on the disease and could also affect the way patients with other health conditions, like cancer, who are prone to developing cardiovascular issues, are diagnosed and treated. “White blood cells play a key role in fueling adipose tissue (fat) inflammation and insulin resistance in obesity and also promote the clogging of arteries, or atherosclerosis, setting the stage for heart attack and stroke...
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