Category Health/Medical

Guided Ultrasound + Nanoparticle Chemotherapy Cures Tumors in Mice

Clockwise from top left: A tumor (blue arrows) is heated with ultrasound (red dashed line); heat map of tumor during treatment; PET scan shows nanoparticles in surviving tumor margin; bright contrast agent shows area damaged by heat. Credit: Andrew Wong/UC Davis

Clockwise from top left: A tumor (blue arrows) is heated with ultrasound (red dashed line); heat map of tumor during treatment; PET scan shows nanoparticles in surviving tumor margin; bright contrast agent shows area damaged by heat. Credit: Andrew Wong/UC Davis

Thermal ablation with magnetic resonance-guided focused ultrasound surgery (MRgFUS) is a noninvasive technique for treating fibroids and cancer. New research from UC Davis shows that combining the technique with chemotherapy can allow complete destruction of tumors in mice. MRgFUS combines an ultrasound beam that heats and destroys tissue with a magnetic resonance imaging to guide the beam and monitor the effects of treatment...

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Genetically Modified mice reveal Secret to a Painless Life

People born with a rare genetic mutation are unable to feel pain, but previous attempts to recreate this effect with drugs have had surprisingly little success. Using mice modified to carry the same mutation, researchers have now discovered the recipe for painlessness. Credit: Courtesy of David Bishop, UCL

People born with a rare genetic mutation are unable to feel pain, but previous attempts to recreate this effect with drugs have had surprisingly little success. Using mice modified to carry the same mutation, researchers have now discovered the recipe for painlessness. Credit: Courtesy of David Bishop, UCL

People born with a rare genetic mutation are unable to feel pain, but previous attempts to recreate this effect with drugs have had surprisingly little success. Using mice modified to carry the same mutation, researchers have now discovered the drug recipe for painlessness.

In 2006, it was shown that sodium channel Nav1.7 is particularly important for signalling in pain pathways and people born with non-functioning Nav1.7 do not feel pain. Drugs that block Nav1...

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Neuroscience explains why we are Quick to Blame people for their actions, but Slower to give them Credit

As shown in this functional MRI image, the amygdala, a part of the brain involved in processing emotions, is more active in people who are blaming others for their negative actions. Credit: Lawrence Ngo

As shown in this functional MRI image, the amygdala, a part of the brain involved in processing emotions, is more active in people who are blaming others for their negative actions. Credit: Lawrence Ngo

Judgment hinges on whether action was intentional or unintentional. We constantly read others’ intentions in what they do, especially political candidates. The Duke study is “the first to use neuroscience research tools to try to explain why people are biased toward treating negative actions as intentional but positive actions as unintentional,” said Lawrence Ngo.

Take this scenario commonly used in the field of experimental philosophy: The CEO knew the plan would harm the environment, but he did not care at all about the effect the plan would have on the environment...

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How much TV you watch as a Young Adult may affect Midlife Cognitive Function

 

Few studies have investigated the association between physical activity in early adulthood and cognitive function later in life. Watching a lot of TV and having a low physical activity level as a young adult were associated with worse cognitive function 25 years later in midlife. The study of 3,247 adults (ages 18 to 30) used a questionnaire to assess television viewing and physical activity during repeated visits over 25 years. High television viewing was defined as watching TV for more than 3 hours per day for more than 2/3 of the visits and exercise was measured as units based on time and intensity. Cognitive function was evaluated at year 25 using three tests that assessed processing speed, executive function and verbal memory.

Participants with high television viewing during 25 ...

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