Category Health/Medical

Chondroitin Outperforms Celecoxib in Knee Osteoarthritis study

Chondroitin sulfate glycosaminoglycans are two-sugar repeating polymers that display diverse sulfation patterns in vivo.

Chondroitin sulfate glycosaminoglycans are two-sugar repeating polymers that display diverse sulfation patterns in vivo.

For the 1st time, chondroitin sulfate has been more successful than celecoxib in reducing the long-term progression of knee osteoarthritis (OA), according to new research findings. Chondroitin sulfate, more commonly called chondroitin, has long been the subject of debate when it comes to its usefulness in treating OA. Canadian researchers recently explored how this treatment would affect how OA progresses as well as how it compared to celecoxib (Celebrex®).

“We felt the present study was necessary in order to establish – using the most recent imaging technology available, quantitative magnetic resonance imaging (qMRI) – whether chondroitin sulfate can truly and effectiv...

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Cholesterol-lowering ‘Portfolio Diet’ also reduces Blood Pressure

Diet has already impacted guidelines in Canada and Europe. The research, published today in Nutrition, Metabolism and Cardiovascular Disease, was a secondary analysis of data collected for a 2011 study on the effect of the ‘portfolio diet’ on cholesterol. The portfolio diet lowered blood pressure by ~2%, when compared with another diet recommended to reduce hypertension.

The portfolio diet includes foods that are scientifically-proven to lower cholesterol including mixed nuts, soy protein, plant sterols (found in vegetable oils and leafy vegetables) and viscous fiber (found in oats, barley and eggplant). The comparison method, a dietary approach to stopping hypertension, or DASH diet, emphasizes fruit, vegetables and whole grains, reduced meat and dairy intake, and eliminating snack food.

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Protein Movement of Hair bundles in the Inner Ear may Preserve Hearing for life

Each single hair bundle within the live zebrafish ear contains fascin 2b fused with green fluorescent protein. In this time coarse, the fascin 2b molecules migrate to other regions of the bundle within 220 seconds. Credit: Cell Reports: Adapted from Figure 1 in "The Stereociliary Paracrystal is a Dynamic Cytoskeletal Scaffold In Vivo"

Each single hair bundle within the live zebrafish ear contains fascin 2b fused with green fluorescent protein. In this time coarse, the fascin 2b molecules migrate to other regions of the bundle within 220 seconds. Credit: Cell Reports: Adapted from Figure 1 in “The Stereociliary Paracrystal is a Dynamic Cytoskeletal Scaffold In Vivo”

Finding holds promise for repairing damaged hearing. Hearing is made possible when hair bundles protruding from hair cells capture the energy of sound waves, converting them into electrical signals that stimulate the auditory nerve to the brain. The hair bundles are made up of stereocilia, which sway in unison with other stereocilia, and remain permanently with us throughout our lives...

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Iron Supplementation: When Less is really More

Legumes such as beans, soy or lentils are good sources of iron. (Image: www.colourbox.com)

Legumes such as beans, soy or lentils are good sources of iron. (Image: www.colourbox.com)

Therapeutic iron supplements may be less effective when given in brief intervals: A peptide molecule blocks iron absorption in the intestine even 24 hours after the iron administation. Anemia is often the result of an iron deficiency. In such cases the patients, who are typically female, will be prescribed iron supplements to be taken daily.

As soon as iron enters the body, hepcidin production begins in the liver. This tiny protein, which is composed of just 25 amino acid building blocks, then is released into the bloodstream and reaches the intestine, where one of its functions is to regulate the amount of iron absorbed into the body through the cells of the gastrointestinal tract...

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