Category Health/Medical

Silk Bio-ink could help advance Tissue Engineering with 3D Printers

Scientists have developed a silk-based, 3-D printer ink for use in biomedical implants or tissue engineering. Credit: American Chemical Society

Scientists have developed a silk-based, 3-D printer ink for use in biomedical implants or tissue engineering. Credit: American Chemical Society

Silk bio-ink is useful for more complex tissues with versatile functions eg tissues that can be loaded with pharmaceuticals. In the past finding an ideal bio-ink has stalled more complicated tissue engineering progress till now. Most inks currently being developed for 3D printing are made of thermoplastics, silicones, collagen and gelatin or alginate. But there are limits to how these inks can be used. For example, the temperatures, pH changes and crosslinking methods that may be required to toughen some of these materials can damage cells or other biological components that researchers want to add to the inks.

Silk-based bioinks were developed for 2D and 3D printing. By incorporating nontoxic polyols into silk solutions, two-part formulations with self-curing features at room temperature were generated. By varying the formulations the crystallinity of the silk polymer matrix could be controlled to support printing in 2D and 3D formats interfaced with CAD geometry and with good feature resolution. The self-curing phenomenon was tuned and exploited in order to demonstrate the formation of both structural and support materials.

Silk-based bioinks were developed for...

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Completely Paralyzed Man Voluntarily Moves his Legs

Courtesy of Mark Pollock Mark Pollock and trainer Simon O’Donnell

Mark Pollock and trainer Simon O’Donnell Courtesy of Mark Pollock

Robotic step training, noninvasive spinal stimulation enable patient to take thousands of steps. A 39yo man who had had been completely paralyzed for 4 years was able to voluntarily control his leg muscles and take many steps in a robotic exoskeleton during 5 days of training with the aid of the robotic device combined with a novel noninvasive spinal stimulation pattern that does not require surgery, UCLA scientists report.

This is the first time that a person with chronic, complete paralysis has regained enough voluntary control to actively work with a robotic device designed to enhance mobility...

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New Technology Transforms Cell Phone into High-powered Microscope

Gerard Coté, professor of biomedical engineering and director of the Texas A&M Engineering Experiment Station’s Center for Remote Health Technologies and Systems. Credit: Texas A&M University

Gerard Coté, professor of biomedical engineering and director of the Texas A&M Engineering Experiment Station’s Center for Remote Health Technologies and Systems. Credit: Texas A&M University

It could significantly improve malaria diagnoses, Rx in developing countries that often lack the resources to address the life-threatening disease. The add-on device, which is similar in look and feel to a protective phone case, uses a smart phone’s camera features to produce high-resolution images of objects 10X smaller than the thickness of a human hair, says Prof Gerard Coté who developed the mobile-optical-polarization imaging device (MOPID).

MOPID is capable of accepting a small cartridge containing a patient’s blood-smear sample, which is then imaged using polarized light in order to detect ...

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1st-of-its-kind exploratory study ID’s potential Gene a/w Most Common Cause of Liver Damage

NASHprogression

NAS/ Nonalcoholic‬ ‪‎fatty‬ liver disease progression

Nonalcoholic fatty liver disease is the most common cause of liver damage. In this study, TGen scientists sequenced microRNAs from liver biopsies, spelling out their biochemical molecules to identify several potential gene targets associated with NAFLD-related liver damage.

The miRNAs – RNA molecules that regulate gene expression – were obtained from liver biopsies of 30 female candidates for gastric bypass surgery: 15 with, and 15 without, NAFLD liver damage. Using the most advanced technology to refine the data, researchers identified several potential gene targets associated with NAFLD-related liver damage...

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