Category Health/Medical

Diet, Microbes and Fat: A new pathway controlling levels of body fat and cholesterol

Diet, microbes and fat: A new pathway controlling levels of body fat and cholesterol
Lipid accumulation in a murine model of fatty liver disease, visualized by color-enhanced lipid droplets (pink) in liver tissue (green). Superimposed chemical structure of a newly discovered bile acid conjugate. Credit: Dr. Mohammad Arifuzzaman, Dr. Christopher Parkhurst, Dr. Frank Schroeder, and Dr. David Artis.

Beneficial gut microbes and the body work together to fine-tune fat metabolism and cholesterol levels, according to a new preclinical study by investigators from Weill Cornell Medicine and the Boyce Thompson Institute at Cornell University’s Ithaca campus.

The research is published in the journal Nature.

The human body has co-evolved with the beneficial microbes that live in the gut (termed the microbiota), resulting in mutually favorable relationships that aid in the d...

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Words Activate Hidden Brain Processes Shaping Emotions, Decisions and Behavior

Words activate hidden brain processes shaping emotions, decisions, and behavior
Emotional words evoke region- and valence-specific patterns of concurrent neuromodulator release in the human thalamus and cortex. Batten et al/Cell Reports. Credit: Batten et al/Cell Reports

In an unprecedented new study, researchers have shown neurotransmitters in the human brain are released during the processing of the emotional content of language, providing new insights into how people interpret the significance of words.

The work, conducted by an international team led by Virginia Tech scientists, offers deeper understanding into how language influences human choices and mental health.

Spearheaded by computational neuroscientist Read Montague, a professor of the Fralin Biomedical Research Institute at VTC and director of the institute’s Center for Human Neuroscience Resear...

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These 11 Genes may help us Better Understand Forever Chemicals’ Effects on the Brain

A blue gloved hand places a small bottle of liquid into a laboratory machine.
A study led by the labs of University at Buffalo chemistry professors G. Ekin Atilla-Gokcumen and Diana Aga has uncovered some molecular clues about the neurotoxic effects of  per- and polyfluorinated alkyl substances, better known as forever chemicals. Photo: Meredith Forrest Kulwicki/University at Buffalo

Molecular clues about the neurotoxic effects of PFAS. A new study has identified 11 genes that may hold the key to understanding the brain’s response to these pervasive chemicals commonly found in everyday items.

Per- and polyfluorinated alkyl substances (PFAS) earn their “forever chemical” moniker by persisting in water, soil and even the human brain.

This unique ability to cross the blood-brain barrier and accumulate in brain tissue makes PFAS particularly concerning, but t...

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Mediterranean Diet Linked to Improved Memory via Gut Bacteria Changes

Mediterranean diet
The Mediterranean diet focuses on fruits, vegetables, whole grains, olive oil, fish and legumes. Photo by Shutterstock

A new Tulane University study suggests the Mediterranean diet’s brain-boosting benefits may work by changing the balance of bacteria in the gut.

In a study published in Gut Microbes Reports, researchers at Tulane University School of Medicine found that subjects following a Mediterranean diet developed distinctly different gut bacteria patterns compared to those eating a typical Western diet. These bacterial changes correlated with better memory and cognitive performance.

“We’ve known that what we eat affects brain function, but this study explores how that could be happening,” said lead author Rebecca Solch-Ottaiano, Ph.D...

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